A Comparative Study Between Ultrasound Guided External Oblique Intercostal Plane (EOIP) Block and Erector Spinae Plane (ESP) Block for Postoperative Analgesia in Upper Abdominal Surgeries

Block Clinical Trial

Official title:

A Comparative Study Between Ultrasound Guided External Oblique Intercostal Plane (EOIP) Block and Erector Spinae Plane (ESP) Block for Postoperative Analgesia in Upper Abdominal Surgeries

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06097286
• Other study ID #: MD80/2023
• Status: Not yet recruiting
• Phase: N/A
• Start date: November 1, 2023
• Est. completion date: June 1, 2024

Study information

• Verified date: March 2023
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Upper abdominal incisions, such as the oblique subcostal laparotomy, can cause severe pain and can lead to significant respiratory impairment.

Erector spinae plane (ESP) block is the deposition of local anaesthetic (LA) in the interfascial plane at the paraspinal region. It provides effective visceral and somatic analgesia.

External oblique intercostal plane (EOIP) block is a newly described block at which local anaesthetic (LA) is deposited in the interfascial plane deep to external oblique muscle at the sixth intercostal space. It provides blockade of the thoracoabdominal nerves at the level of T6 to T10.

In this study, the investigators compare between ultrasound (US) guided external oblique intercostal plane block and erector spinae plane block, in providing postoperative analgesia for upper abdominal surgeries

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 75
• Est. completion date: June 1, 2024
• Est. primary completion date: April 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients with American Society of Anesthesiologists physical status (ASA) I and II.

• Both sex.

• 20 to 60 years old patients.

• upper abdominal surgeries.

Exclusion Criteria:

• Refusal of the patient to consent.

• Patients with ASA status III or IV

• Patients with bleeding disorders and coagulopathy (INR=1.6 & PTT=50 sec).

• Infection at the injection site.

• Allergy to local anesthetics.

• Patients with ages less than 20 or more than 60

• Patients with pre-existing myopathy or neuropathy.

• Patients with chronic pain syndromes.

• Patients with history of long acting opioids or steroids preoperatively.

Related Conditions & MeSH terms

• Block

Intervention

Procedure:
• external oblique intercostal plane block
o EOIP Group (?=25): Patients will receive ultrasound guided External oblique intercostal plane block with 20 ml of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a total volume of 20 ml.) at the end of procedure, unilaterally or bilaterally according to the surgery.
• erector spinae plane block
o ESP Group (?=25): Patients will receive ultrasound guided Erector spinae plane block with 20 ml of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a total volume of 20 ml.) at the end of procedure, unilaterally or bilaterally according to the surgery.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	amount of total 24 hour pethidine consumption (mg) .	to measure total 24 hour pethidine consumption postoperatively.	24 hours postoperatively
Secondary	visual analogue scale (VAS) at rest and movement.	recorded postoperative immediately and 2, 4, 6, 8, 12, 18 and 24 hours. The Visual Analogue Scale (VAS) measures pain intensity. The visual analogue scale (VAS) consists of a 10 cm line, with two end points representing 0 (no pain) and 10 (pain as bad as it could possibly be).	24 hours postoperatively
Secondary	mean arterial blood pressure (MAP)	recorded postoperative immediately and 2, 4, 6, 8, 12, 18 and 24 hours	24 hours postoperatively
Secondary	heart rate (HR)	recorded postoperative immediately and 2, 4, 6, 8, 12, 18 and 24 hours	24 hours postoperatively
Secondary	incidence of postoperative complications (nausea and vomiting)	recorded postoperative immediately and 2, 4, 6, 8, 12, 18 and 24 hours	24 hours postoperatively
Secondary	time to start mobilization	recorded postoperative immediately and 2, 4, 6, 8, 12, 18 and 24 hours	24 hours postoperatively