Blueberry Effects on Dark Vision and Glare Recovery

Blindness and Low Vision Clinical Trial

Official title: Placebo-controlled Cross-over Studies Examining Blueberries Effects on Dark Vision and Recovery After Photo-bleaching

Status Completed

Clinical Trial Summary

Clinical evidence for effects of plant anthocyanins on vision, and particularly night vision is controversial. Two clinical trials were conducted to investigate whether blueberry juice consumption affected visual dark adaptation, functional night vision, and recovery after photo-bleaching of the retina. One trial (S2) employed a 3 week intervention and washout period, and two doses of blueberries plus a placebo. The other trial (L1) employed a 12 week intervention plus an 8 week washout and tested one blueberry juice dose against a juice placebo.

Clinical Trial Description

Vision Tests: 1. Dark adaptometry, 2. scotopic visual acuity, 3. scotopic contrast sensitivity, 4. rod/cone conversion, 5. recovery after retinal photobleaching ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Blindness
• Blindness and Low Vision
• Vision, Low

• NCT number: NCT01942746
• Study type: Interventional
• Source: Atlantic Food and Horticulture Research Center
• Status: Completed
• Phase: N/A
• Start date: July 2005
• Completion date: July 2006