Bleeding Risk in CVCs

Status Completed

Clinical Trial Summary

Since many of the patients in an intensive care unit suffer from disorders of hemostasis, bleeding is a main concern applying central venous catheters. Even if there are some data indicating elevated international normalized ratio may not increase the risk of bleeding no clear cut-off has been defined so far. An INR > 1.5 is generally considered to increase the risk of bleeding. Furthermore, many authors consider platelets below 50 x 109 /l as a contra-indication to CVC cannulation, since there are some data this may increase the risk of bleeding. Therefore platelet transfusion before venous puncture is suggested. In our clinical experience INR > 1.5 and platelets < 50 x 109 /l do not correlate with increased risk of bleeding. The aim of this study is to demonstrate, that coagulopathy, defined by INR and platelet count, is not decisive for bleeding.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00448188
Study type	Interventional
Source	Heidelberg University
Contact
Status	Completed
Phase	N/A
Start date	November 2005
Completion date	March 2007

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04058223` - Comparison of the Short-term Outcomes of Using DST and PPH Staplers in the Treatment of Grade III and IV Hemorrhoids
Completed	`NCT03678168` - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries	N/A
Completed	`NCT05669313` - The Effects of Hypothermia and Acidosis on Coagulation During Treatment With Rivaroxaban Measured With ROTEM
Completed	`NCT04590898` - Peri-device Leakage Closure After LAAO
Active, not recruiting	`NCT05563883` - Atrial Fibrillation and Cancer: a Nationwide French Cohort Study
Not yet recruiting	`NCT04537533` - Tranexamic Acid Infusion in Low Dose Versus in High Dose for Reducing Blood Loss in Radical Cystectomy Operations	Phase 4
Withdrawn	`NCT02851940` - Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids	N/A
Completed	`NCT02722720` - Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral	N/A
Recruiting	`NCT02279186` - Effectiveness of Intravenous Tranexamic Acid in Reducing Blood Loss During and After Cesarean Section	Phase 4
Active, not recruiting	`NCT02244853` - Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease	N/A
Completed	`NCT02980497` - Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study	N/A
Completed	`NCT02245854` - Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps	N/A
Completed	`NCT02092415` - Assessment of Limb Perfusion During Junctional Tourniquet	N/A
Not yet recruiting	`NCT01438736` - Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?	Phase 4
Completed	`NCT00515541` - Lovaza's Effect on the Activation of Platelets	Phase 2
Completed	`NCT00143715` - Oral Vitamin K for Warfarin Associated Coagulopathy	Phase 3
Terminated	`NCT03954314` - DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery	Phase 3
Recruiting	`NCT05945680` - Tranexamic Acid in Breast Esthetic Surgery.	Phase 4
Recruiting	`NCT03783182` - Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy	Phase 4
Not yet recruiting	`NCT05464394` - Peroperative Administration of Tranexamic Acid in Roux-en-Y Gastric Bypass and One-anastomosis Gastric Bypass	Phase 3