Bleeding Clinical Trial
Official title:
Association Between Viscoelastic Tests-Guided Therapy With Synthetic Factor Concentrates And Allogenic Blood Transfusion In Liver Transplantation: A Before-After Study
BACKGROUND: Perioperative bleeding and transfusion are important causes of morbidity and
mortality in patients undergoing liver transplantation. The aim of this study is to assess
whether viscoelastic tests-guided therapy with the use of synthetic factor concentrates
impact transfusion rates of hemocomponents in adult patients undergoing liver
transplantation.
METHODS: This is an interventional before-after comparative study. Patients undergoing liver
transplantation before the implementation of a protocol using thromboelastometry and
synthetic factor concentrates were compared to patients after the implementation. Primary
outcome was transfusion of any hemocomponents. Secondary outcomes included: transfusion of
red blood cells (RBC), fresh frozen plasma (FFP), cryoprecipitate or platelets, clinical
complications, length of stay and in-hospital mortality.
n/a
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