Bladder Cancer Clinical Trial
Official title:
Treatment of High-risk Non-muscle Invasive Bladder Cancer With IMUNO BGC Moreau RJ as Prophylaxis of Recurrence and Progression.
Bladder cancer is the fourth reason of neoplasia in our environment, there are 25 new cases
diagnosed per 100,000 inhabitants each year. To decrease the recurrence there are two
standardized treatments: Mitomycin as chemotherapy drug and BCG *Bacile Calmette-Guérin" as
immunotherapy drug.
BCG Moreau strain is not authorized by AEMPS, it was developed in Brazil and this country has
extensive experience in treatment of non-muscle invasive bladder cancer with BCG Moreau, also
BCG Moreau Rio de Janeiro make same immunological reaction as TICE, but with less adverse
events. Thus, BCG Moreau RJ treatment could be used more time than TICE with the same dose,
keeping immunologic status and better prophylaxis of recurrence or progression results for
the patient.
Each patient will be instillated via transurethral each time with 80 mg of IMUNO BCG Moreau
RJ. There are 15 instillations during the clinical trial, 6 instillations on induction phase
and 9 will be performed during maintaince phase.
n/a
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