Bladder Cancer Clinical Trial
Official title:
Trimodal Prehabilitation for Cystectomy Patients to Enhance Post-operative Care: A Randomized Control Trial
Trimodal prehabilitation is a preoperative three-tiered (trimodal) approach to optimizing
physical and mental health. It has been found to successfully improve functional recovery in
patients undergoing colorectal surgery following an evidence-based enhanced-recovery pathway
(ERP). It is unknown whether the same program is effective in patients undergoing a similar
surgery for bladder cancer (radical cystectomy).
Objective: To evaluate the appropriateness of a standardized prehabilitation program for
implementation into an enhanced recovery pathway for cystectomy patients and determine
whether prehabilitation facilitates earlier recovery of functional capacity.
Hypothesis: Prehabilitation will ultimately improve recovery of functional capacity, clinical
and patient-centered outcomes in patients undergoing radical cystectomy for bladder cancer.
Design: Participants will follow an 8-week trimodal prehabilitation program consisting of
exercise therapy combined with nutritional counseling, protein supplementation, and
psychological care; they will be compared to a cohort of participants following ERP care
alone.
Conclusion: The proposal will provide insight into the feasibility and effectiveness of
trimodal prehabilitation for radical cystectomy patients and may ultimately lead to improved
clinical outcomes and reduced morbidity.
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