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Clinical Trial Summary

To demonstrate that radiotherapy treatments for bladder cancer can be delivered with greater accuracy using a new planning method and that this method can be used simply and effectively by those delivering treatment.


Clinical Trial Description

This study integrates a novel adaptive planning methodology, Adaptive-Planning Organ LOcalisation (A-POLO), with optimised margins and cone beam CT technology for improving the accuracy of radiotherapy treatment delivery.

The previous study (CCR2873, REC 07/Q0801/13) evaluated the use of cone beam CT in radiotherapy for bladder cancer. A larger than expected number of bladder radiotherapy treatments were seen to have been delivered with some element of geographic miss. Using the novel adaptive planning method these fractions of radiotherapy could have been correctly treated. The feasibility of this method has been proven in the previous study, particularly it has been shown that this method is appropriate and provides a simple solution to the problem. It can be carried out by the radiographers at the treatment unit without adding extra time to the treatment. ;


Study Design

Intervention Model: Single Group Assignment, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01000129
Study type Interventional
Source Royal Marsden NHS Foundation Trust
Contact Dr Robert Huddart
Phone 02086613457
Email robert.huddart@icr.ac.uk
Status Recruiting
Phase Phase 2
Start date January 2009
Completion date December 2010

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