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Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and Midazolam

Biological Availability Clinical Trial

Official title:
Open-label, Randomized, Fixed Sequence Cross-over Study With Five Parallel Treatment Arms and Three Treatment Periods to Quantify the Drug-drug Interactions of Two Rifampicin Dose Strengths on Four Progestins and a Fixed Progestin-ethinylestradiol Combination Compared With Midazolam in Healthy Post-menopausal Women

Clinical Trial Summary

Quantify the effect of a probe CYP3A4 inducer (Rifampicin) on the pharmacokinetics of levonorgestrel, norethindrone, desogestrel, dienogest, drospirenone,estradiol and midazolam

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03353857
Study type Interventional
Source Bayer
Contact
Status Completed
Phase Phase 1
Start date November 29, 2017
Completion date February 19, 2019
View Details
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