Clinical Trials Logo
  1. Home
  2. Benign Prostate Hyperplasia
  3. NCT01736033

Advanced Benefits of Alpha-blocker Monotherapy on Lower Urinary Tracts Symptoms(LUTS) Patients — ABSOLUTE  

Benign Prostate Hyperplasia Clinical Trial

Official title:
A Multicenter, Randomized, Double-blind, Clinical Study to Investigate the Efficacy and Safety of Treatment With Tamsulosin 0.2mg Mono and Tamsulosin 0.2mg, Finasteride 5mg Combination Therapy in Patients With LUTS/BPH

Clinical Trial Summary

The purpose of this study is to evaluate the clinical efficacy of alpha-blocker monotherapy and alpha-blocker + 5-alpha reductase inhibitor combination therapy in benign prostate hyperplasia patients, and suggest guidelines of the combination therapy.

Clinical Trial Description

Even though it should be decided on patients cautiously under careful consideration about prostate volume, Prostate Specific Antigen(PSA) level, symptom score and maximum uroflow, recently the combination therapy of alpha-blocker and 5-alpha reductase inhibitor has been tried imprudently in Korea.

As a result of several clinical trials which had conducted overseas for releasing the combination drug of alpha-blocker and 5-alpha reductase inhibitor, the superiority of the combination therapy has been proved, however, plenty of patients still don't derive additional profit from it.

Therefore, in this study, the investigators anticipate to meet with meaningful results on the clinical efficacy of alpha-blocker monotherapy and alpha-blocker + 5-alpha reductase inhibitor combination therapy in Korean benign prostate hyperplasia patients, and provide guidelines of the combination therapy. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01736033
Study type Interventional
Source Seoul National University Hospital
Contact
Status Active, not recruiting
Phase Phase 4
Start date February 2012
Completion date June 2017
View Details
See also
  Status Clinical Trial Phase
Completed NCT01942551 - Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride Phase 1
Completed NCT01436877 - Assessing Safety & Efficacy of MediTate Temporary Implant in Subjects With Benign Prostate Hyperplasia N/A
Completed NCT02822924 - Prostate Artery Embolization for Symptomatic Benign Prostatic Hyperplasia N/A
Completed NCT02390882 - A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of HGP0412 and HIP1402 in Patients With BPH Phase 3
Completed NCT02839122 - A Study to Investigate the Pharmacokinetic Drug Interactions Between Dutasteride and Tadalafil in Healthy Male Subjects Phase 1
Not yet recruiting NCT01861041 - Low Dose Bupivacaine Spinal for Trans Uretral Prostatectomy. Phase 4
Completed NCT02332538 - HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH N/A
Completed NCT01835860 - Prostatic Artery Embolization for Benign Prostatic Hyperplasia Phase 2/Phase 3
Completed NCT01665586 - Effective Dose of Dexmedetomidine for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia With or Without Fentanyl by Age Groups: Randomized Comparative Study N/A
Completed NCT02038868 - A Study to Evaluate the Efficacy and Safety of ASP4901 in Patients With Benign Prostate Hyperplasia Phase 2
Completed NCT02506465 - Pivotal Study to Assess the Safety and Effectiveness of the iTind Device N/A
Completed NCT01675895 - Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration Phase 4
Completed NCT02483819 - Changes of the Hemodynamic Profiles on Bio Reactance Technique During TURP in Elderly Patients N/A
Recruiting NCT02827578 - Efficacy and Safety of Tamsulosin/Solifenacin Combination Therapy in Patients With Voiding Symptoms and Moderate to Severe Storage Symptoms Due to Benign Prostate Hyperplasia Phase 3
Completed NCT02352311 - Safety and Pharmacokinetic Characteristics of DKF-313 Phase 1
Completed NCT01494337 - Holmium Laser Enucleation of Prostate(HOLEP) vs Greenlight(XPS) Laser Photoselective Vapo-Enucleation of Prostate(PVEP) Phase 4
Completed NCT01627522 - Evaluation of Finastride Effect in Different Dosage on the Amount of Perioperative Bleeding in Transurthral Resection of Prostate Phase 2/Phase 3
Completed NCT01952912 - Plasmakinetic Enucleation of the Prostate and Open Prostatectomy to Treat Large Prostates N/A
Recruiting NCT02021032 - Post-Marketing Study Using PROLIEVE® for the Treatment of Benign Prostatic Hyperplasia (BPH) Phase 4
Completed NCT00861588 - Effects of Isoflavone in Patients With Watchful Waiting Benign Prostate Hyperplasia N/A