Benign Neoplasm Clinical Trial
Official title:
Application of Virtual Surgical Planning in Mandibular Segmental Resection With Reconstruction Plate
Purpose: Odontogenic tumors, predominantly affecting the mandibular region, pose significant challenges in terms of treatment planning, particularly when requiring segmental mandibular resection. This study aims to evaluate the effectiveness of virtual planning and 3D modeling in comparison to traditional surgical methods for treating mandibular odontogenic tumors, focusing on aspects such as accuracy, clinical outcomes, and patient quality of life. Method: The study is designed as a two-phase investigation. Phase 1 involves in vitro research to create high-precision 3D models and surgical support instruments. Phase 2 consists of a clinical trial with two groups: the Virtual Surgery Group using pre-bent reconstruction plates, 3D mandibular models and surgical guides and the Conventional Surgery Group. Data collection includes assessing model accuracy, comparing clinical outcomes, analyzing postoperative CT scans, and evaluating patient quality of life. Expected Results: Investigators anticipate that the virtual planning and 3D modeling approach will yield more accurate surgical procedures, improved postoperative outcomes, and enhanced patient quality of life compared to traditional methods. This is expected to be particularly beneficial in maintaining the stability of the condyle at the postoperative site, reducing complications related to mandibular function, and potentially reducing the need for additional surgeries. Conclusions: If the investigators study demonstrates the superiority of virtual planning and 3D modeling in treating mandibular odontogenic tumors, it could significantly impact the field of oral and maxillofacial surgery by offering a more precise and effective treatment approach. This could ultimately lead to improved patient outcomes and a reduction in the challenges associated with these complex surgical procedures.
Status | Recruiting |
Enrollment | 30 |
Est. completion date | December 2025 |
Est. primary completion date | November 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Patients indicated for mandibular segment resection and reconstruction plate placement. - Patients in overall good health suitable for undergoing anesthesia. - Patients who consent to the surgery and agree to participate in the study. Exclusion Criteria: - Patients indicated for temporomandibular joint dislocation due to invasive tumor. - Patients with infections in the mandible. - Patients with a history of trauma or surgery in the concave region of the mandible. - Patients with contraindications for surgery due to systemic diseases. - Patients without the conditions for postoperative follow-up and re-examination. |
Country | Name | City | State |
---|---|---|---|
Vietnam | National Hospital of Odonto-Stomatology in Ho Chi Minh City | Ho Chi Minh City | Ho Chi Minh |
Lead Sponsor | Collaborator |
---|---|
University of Medicine and Pharmacy at Ho Chi Minh City |
Vietnam,
Kokubun K, Yamamoto K, Nakajima K, Akashi Y, Chujo T, Takano M, Katakura A, Matsuzaka K. Frequency of Odontogenic Tumors: A Single Center Study of 1089 Cases in Japan and Literature Review. Head Neck Pathol. 2022 Jun;16(2):494-502. doi: 10.1007/s12105-021-01390-w. Epub 2021 Oct 30. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The Accuracy of Occlusion after surgery following virtual surgical planning | Assessment by Clinical Assessment involves observing three areas: the front teeth region, the right posterior teeth region, and the left posterior teeth region.
The scoring scale is as follows: Posterior teeth group: Achieving interlocking: 2 points, achieving contact: 1 point, completely open: 0 points. Anterior teeth group achieving contact: 1 point, completely open: 0 points. Calculate the total score attained and classify the bite joint based on the criteria: Good: = 4, Average: 2 - 3, Poor: < 2 |
Baseline, 1 week, 24 weeks | |
Primary | The Accuracy of Condylar position after surgery following virtual surgical planning | Assessment by CT scan the condylar position after surgery following the change anatomical lankmarks. Value of Condylar Deviation: The range between -12% to +12% is Center position, The range +12% is Forward position, and the range < -12% is Rearward position | Baseline, 1 week, 24 weeks |
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