Changes in Bacterial Flora Among Patients With Pelvic Bedsores: a Prospective Pilot Study — EscaFlor  

Bedsore Clinical Trial

Official title: Changes in Cutaneous, Digestive and Urinary Bacterial Flora Among Patients With Pelvic Bedsores: a Prospective Pilot Study

Status Completed

Clinical Trial Summary

The main objective of this study is to characterize the evolution (over a period of 28 days) of superficial and deep bacterial skin flora in patients with stage 3 or 4 sacral pressure ulcers (bedsores). Changes in terms of pathogenic, potentially pathogenic and non-pathogenic bacterial species at the intra-individual and population levels.

Clinical Trial Description

The secondary objectives of this study are:

A. To compare bacterial communities collected from superficial versus deep samples of stage 3 or 4 sacral bedsores using metagenomics and standard culturing methods.

B. To characterize the evolution of digestive bacterial flora in the same patients over a period of 28 days. Changes in terms of pathogenic, potentially pathogenic and non-pathogenic will be described, as well as the appearance of resistance phenotypes.

C. To characterize the evolution of urinary bacterial flora in the same patients over a period of 28 days. Changes in terms of pathogenic, potentially pathogenic and non-pathogenic will be described, as well as the appearance of resistance phenotypes. ;

Related Conditions & MeSH terms

• Bedsore
• Pressure Ulcer

• NCT number: NCT02055729
• Study type: Observational
• Source: Centre Hospitalier Universitaire de Nimes
• Status: Completed
• Start date: May 11, 2015
• Completion date: September 21, 2017