Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation

Basal Cell Carcinoma Clinical Trial

Official title:

Observational Study of Basal Cell Carcinoma Operated at Montpellier University Hospital and Millau Hospital From February 2020 to February 2021 - Study of Correlation Between Localisation and Recurrence, and Other Criterias

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04795297
• Other study ID #: RECHMPL21_0156
• Status: Completed
• Start date: February 1, 2020
• Est. completion date: February 20, 2021

Study information

• Verified date: March 2021
• Source: University Hospital, Montpellier
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected. All the recurrences of BCC were searched from the medical records (or histopathology request form).

From 804 BCC, 48 were recurrent BCC with or without complete first resection. Patients with recurrent BCC were contacted to obtain agreement and more informations about the first resection and some clinical informations like sun exposure and phototype.

The statistical analysis focused on the localisation of recurrent BCC (with a complete first resection) compared to localisations of primary BCC in this population. The goal was to identified localisations with an increased risk of recurrences.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 804
• Est. completion date: February 20, 2021
• Est. primary completion date: February 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 16 Years to 99 Years

Eligibility

Cohort :

Inclusion criteria:

• Patients with resected BCC

Exclusion criteria:

• Biopsies of BCC,

• revised surgery of incomplete resection.

Cases :

Inclusion criteria:

-Recurrent BCC with complete first resection

Exclusion criteria:

• Recurrent BCC with incomplete first resection, Patients with Gorlin syndrome (a genetic disease that increase risk of BCC)

Related Conditions & MeSH terms

• Basal Cell Carcinoma
• Carcinoma
• Carcinoma, Basal Cell

Locations

Country	Name	City	State
France	Uhmontpellier	Montpellier

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	- Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC	- Determined For each localisation the number of primary and recurrent BCC and analysis of localisation with higher risk of BCC	1 day
Secondary	Analysis of correlation between localisation and histology characteristics	Analysis of correlation between localisation and histology characteristics	1 day
Secondary	Analysis of correlation between histological type and recurrence risk	Analysis of correlation between histological type and recurrence risk	1 day
Secondary	Analysis if there is a difference between first resection histological type and the recurrent histological type	Analysis if there is a difference between first resection histological type and the recurrent histological type	1 day