Microarray Analysis of microRNA Expression in Basal Cell Carcinoma

Status Completed

Clinical Trial Summary

Perturbations in microRNA (miRNA) expression profiles has been reported for a variety of cancers. This study will be an exploratory analysis of miRNA expression in basal cell carcinoma by miRNA expression profiling using microarrays.

Clinical Trial Description

Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR). ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01498250
Study type	Observational
Source	Ruhr University of Bochum
Contact
Status	Completed
Phase	N/A
Start date	November 2011
Completion date	December 2011

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04552990` - Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma	Phase 2
Completed	`NCT04229277` - Fast Track Diagnosis of Skin Cancer by Advanced Imaging	N/A
Completed	`NCT05608902` - Structural Description of Skin Biopsies With Dynamic Full-field Optical Coherence Tomography on Suspected Basal Cell Carcinoma Lesions, a Pilot Study (DOCTOBA)
Completed	`NCT05077033` - Intratumoral phIL12 GET	Phase 1
Active, not recruiting	`NCT04928222` - Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II)	Phase 1/Phase 2
Recruiting	`NCT04929535` - Hydrogen Peroxide Trial to Investigate the Efficacy of 30%H2O2 as a Topical Application Before Definitive Treatment	Phase 2
Completed	`NCT02662244` - Long-pulsed 1064 nm Nd:YAG Laser Treatment of Basal Cell Carcinoma	N/A
Completed	`NCT00959647` - A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study	Phase 2
Completed	`NCT00793169` - Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery
Completed	`NCT00586040` - Photochemical Tissue Bonding	Phase 2
Completed	`NCT00473343` - Metvix PDT in Participant With "High Risk" Basal Cell Carcinoma	Phase 3
Active, not recruiting	`NCT06024629` - cOCT Versus LC-OCT for Diagnosing Basal Cell Carcinoma: a Diagnostic Cohort Study
Not yet recruiting	`NCT05324202` - New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management	N/A
Withdrawn	`NCT04099446` - A Non-Interventional Pilot Study to Explore the Skin Microbes in Skin Cancer
Completed	`NCT02902822` - Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo	N/A
Completed	`NCT01201915` - A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449) in Operable Basal Cell Carcinoma	Phase 2
Completed	`NCT01208831` - An East Asian Study of LDE225	Phase 1
Completed	`NCT01260987` - Fractional CO2 Laser Assisted Photodynamic Therapy	Phase 2/Phase 3
Completed	`NCT01014819` - A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions	N/A
Completed	`NCT00472043` - PDT With Metvix 160 mg/g Cream Versus PDT With Placebo Cream in Patients With Primary Nodular Basal Call Carcinoma	Phase 3