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Basal Cell Carcinoma clinical trials

View clinical trials related to Basal Cell Carcinoma.

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NCT ID: NCT02580916 Completed - Clinical trials for Squamous Cell Carcinoma

Utility of the Skin Cancer Quality of Life Impact Tool

SCQOLIT
Start date: July 2015
Phase: N/A
Study type: Interventional

Background: Patient-reported outcome measures (PROMs) provide validated evidence of health and quality of life (QoL) from the patient perspective. Several national PROMs programmes have been implemented in the National Health Service - specifically for common elective procedures. Local implementation is varied across settings and populations. The incidence of non-melanoma skin cancer (NMSC) is rapidly increasing, posing considerable burden on UK healthcare resources, yet there is limited evidence of use of PROMs in NMSC and little information about patients' perceived health and QoL. Objectives: This study will explore feasibility of implementing a skin cancer-specific PROM - Skin Cancer Quality of Life Impact Tool (SCQOLIT) for NMSC. Methods: Three hundred patients with a pathological diagnosis of NMSC undergoing all treatment modalities will be recruited to complete SCQOLIT questionnaires at baseline, at 3, 6 and 9 months. Participation and response rates, missing data and individual change scores will be analysed. Staff and patients will be interviewed to explore acceptability and feasibility of collecting PROMs data. Results: Interim results of the project to date will be presented. Feasibility will be assessed by evaluating number of eligible patients, number of consenting patients, reasons for not consenting and participant number. Individual longitudinal change in scores, response rates and psychometric properties of the SCQOLIT will be reported. Implications: Acceptability and feasibility of the SCQOLIT tool has never been rigorously assessed in Dermatology clinics. A validated NMSC-specific PROM would help standardize multi-centred trials, allow robust evaluation of quality of care and more appropriately direct healthcare resources to improve QoL in patients with NMSC.

NCT ID: NCT02438644 Completed - Clinical trials for Basal Cell Carcinoma

Observational Study of Vismodegib (Erivedge) in Patients Treated in Argentina

Start date: June 30, 2015
Phase: N/A
Study type: Observational

This observational, noninterventional study is designed to further characterize the effectiveness and safety profile of vismodegib (Erivedge) in Argentine patients. Only patients with locally advanced basal cell carcinoma (laBCC) or metastatic basal cell carcinoma (mBCC) will be considered in the effectiveness analysis. Study duration is estimated to be approximately 12 months.

NCT ID: NCT02409628 Completed - Clinical trials for Squamous Cell Carcinoma

EktoTherix™ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds

Start date: April 23, 2015
Phase: N/A
Study type: Interventional

The purpose of study is to assess the safety and performance of EktoTherix™ Tissue Repair Scaffold in the treatment of full-thickness, dermatologic wounds created by the surgical removal of non-melanoma skin cancers. EktoTherix™ is a medical device developed by Neotherix Limited, manufactured by the polymer processing technique of electrospinning. Described as a "tissue scaffold", EktoTherix is placed into the surgical wound to help the patients' own cells repair the wound, enhancing healing and improving quality (including cosmetic outcome). The tissue scaffold is completely absorbed by the body during the healing process, which means that there is no need to remove it when the wound is healed. All patients recruited into this study are treated with EktoTherix, are seen weekly until they heal and seen again at the final follow-up visit three months post-surgery. The investigators hypothesise that the use of EktoTherix will increase incidence of complete healing and result in an overall better cosmetic result of the healed wound.

NCT ID: NCT02371967 Completed - Clinical trials for Basal Cell Carcinoma

A Study to Assess the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Advanced Basal Cell Carcinoma (BCC)

ROSETT
Start date: April 8, 2015
Phase:
Study type: Observational

This prospective, observational, cohort study is designed to assess the effectiveness and safety outcomes of vismodegib and to assess actual day-to-day disease and participant management by the physician.

NCT ID: NCT02296970 Completed - Clinical trials for Basal Cell Carcinoma

An Observational Study to Determine the Clinical Cure Rate of Therapeutic up Front Shave Removal of Basal Cell Carcinoma of the Skin With Long Term Follow up to Evaluate Recurrence

Start date: December 2014
Phase:
Study type: Observational

Determine the effectiveness of a deep shave removal as a definitive treatment for basal cell carcinoma (BCC) without the need for a follow up surgical procedure.

NCT ID: NCT02158650 Completed - Clinical trials for Basal Cell Carcinoma

Video-Based Treatment Options for Basal Cell Carcinoma

Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if presenting treatment options to basal cell carcinoma patients in video format will improve efficiency and allow patients to receive consistent, comprehensive, visually-depicted treatment option information to improve patient quality of care. Patients can learn more about treatment options as they are depicted visually so as to better assist them in understanding treatment risks and benefits to confidently make a well-informed decision. Primarily, the study will evaluate efficiency when using the education video medium. The study will also evaluate the effectiveness of the video medium as an aid to decision making in addition to standard of care in comparison to the standard of care alone. Additionally, the study will evaluate both patients' and dermatologists' satisfaction of the educational intervention.

NCT ID: NCT02125669 Completed - Clinical trials for Basal Cell Carcinoma

Pulsed Dye Laser in Treating Superficial Basal Cell Carcinomas

Start date: November 2012
Phase: N/A
Study type: Interventional

Pulsed dye laser (PDL) treatments have been suggested to be a safe and effective therapeutic approach for treating basal cell carcinomas. Robust supporting evidence is, however, lacking due to inconsistent design of available studies. The purpose of this study is to evaluate the PDL's efficacy and safety in treating superficial basal cell carcinoma (sBCC) at low risk anatomical sites in an evidence based study setting.

NCT ID: NCT02120677 Completed - Clinical trials for Basal Cell Carcinoma

Topical Itraconazole in the Treatment of Basal Cell Carcinoma

Start date: May 2014
Phase: Early Phase 1
Study type: Interventional

This research is being done to study the molecular effects of topically applied itraconazole ointment on the growth of basal cell carcinomas.

NCT ID: NCT02100111 Completed - Clinical trials for Basal Cell Carcinoma

An Analysis of Treatment Patterns and Outcomes for Basal Cell Carcinoma (BCC) Cancer Participants

Start date: January 1, 2005
Phase: N/A
Study type: Observational

This multi-center, observational study involves reviewing the medical records of approximately 100 adult participants diagnosed with advanced BCC from 01 January 2005 until 31 December 2010. Participant records will be analyzed to identify participant characteristics, treatment patterns and clinical outcomes.

NCT ID: NCT01898598 Completed - Clinical trials for Basal Cell Carcinoma

A Study of Vismodegib With Surgery in Patients With Previously Untreated Basal Cell Carcinoma

Start date: February 2014
Phase: Phase 2
Study type: Interventional

This randomized, double-blind, placebo-controlled study will assess the efficacy and safety of vismodegib with surgery in patients with basal cell carcinoma. Patients will be randomized to receive oral daily doses of vismodegib 150 mg or matching placebo. The anticipated time on study drug treatment is 12 weeks.