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Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome — Mouthwash  

Barrett's Esophagus Clinical Trial

Official title:
Pilot Randomized Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal and Gastric Microbiome

Clinical Trial Summary

This is a randomized, open-label pilot study to assess whether treatment with chlorhexidine mouthwash can alter the esophageal and gastric cardia microbiome

Clinical Trial Description

Patients scheduled for upper endoscopy for clinical indications will be randomized to 3 weeks of either no treatment or use of twice daily chlorhexidine mouthwash leading up to the endoscopy. There will be 2-3 study visits, at Day 0 and Day 21, and for those subjects in the mouthwash arm, a final visit 1-2 weeks following the Day 21 visit. Subjects will be required to fast overnight prior to the visits on Days 0 and 21. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02513784
Study type Interventional
Source Columbia University
Contact
Status Completed
Phase N/A
Start date August 2015
Completion date December 2017
View Details
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