Clinical Trials Logo

Bacille Calmette-Guérin clinical trials

View clinical trials related to Bacille Calmette-Guérin.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT02953327 Completed - Innate Immunity Clinical Trials

Testing if BCG (Bacille Calmette-Guérin) Vaccination Can Induce Innate Immune Training in Adult People Above 50 Years of Age in Guinea-Bissau

Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

The propose is to test innate immune training in a pilot study of 40 adults >50 years of age people in Guinea-Bissau. The hypothesis is that BCG vaccination will be associated with increased innate immune training measured as increased cytokine release after in vitro Peripheral Blood Mononuclear Cells (PBMC) stimulation with e.g. Mycobacterium Tuberculosis, Staphylococcus Aureus, Candida Albicans and Streptococcus Pneumoniae.

NCT ID: NCT02447536 Completed - Morbidity Clinical Trials

Trial of Two Strains of BCG

BCGSTRAIN
Start date: December 8, 2014
Phase: Phase 4
Study type: Interventional

The investigators aim to conduct a randomised controlled trial comparing two Bacille Calmette-Guérin (BCG) strains currently used in Guinea-Bissau, the Danish and the Russian, in terms of prevention of neonatal and early life morbidity and mortality, immune responses and adverse events related to BCG vaccination. The primary outcome will be hospital admissions within 6 weeks of age.