Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis

Axial Spondyloarthritis Clinical Trial

Official title:

Exercise Capacity in Axial Spondyloarthritis and Factors Affecting it: a Cross-sectional Controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04706650
• Other study ID #: mugla sitki koçman university
• Status: Completed
• Start date: May 15, 2014
• Est. completion date: October 15, 2014

Study information

• Verified date: January 2021
• Source: Mugla Sitki Koçman University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators aimed to study the associations between exercise capacity and cardiovascular (CV) risk factors in axial spondyloarthritis (axSpA) patients and to determine possible relationships with disease-related variables. Thirty eight patients and 38 controls were recruited in our cross-sectional controlled study. Comprehensive systemic and musculoskeletal examinations were carried out in both of the groups. Cardiovascular risk profile data, ASDAS-CRP, 10-year CV event risk, physical activity levels (IPAQ) were recorded. A maximal treadmill exercise test by Bruce protocol was administered to all participants.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 76
• Est. completion date: October 15, 2014
• Est. primary completion date: October 15, 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• clinical diagnosis of axial SpA

• must be able to walk

Exclusion Criteria:

• established cardiac disease including structural heart diseases,

• uncontrolled hypertension,

• cardiac rhythm disorder,

• unstable angina pectoris,

• chronical renal and/or hepatic disease,

• malignancy,

• neuromuscular disease

• musculoskeletal deformity

• the history of an inflammatory arthritis for control group

Related Conditions & MeSH terms

• Axial Spondyloarthritis
• Exercise Capacity
• Spondylarthritis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Mugla Sitki Koçman University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean difference in exercise capacity of axSpA patients and controls	maximal METs achieved by a maximal treadmill test by Bruce protocol	may- october 2014
Secondary	Mean difference in heart rate recovery of axSpA patients and controls	peak heart rate achieved by maximal exercise minus heart rate at 1st minute of recovery phase	may- october 2014