| Eligibility |
Inclusion Criteria:
1. Male and female non-obese subjects (18kg/M2<BMI<28kg/M2) (age 20-45 years) will be
recruited from the Twin Cities community. All participants will sign informed consent
approved by UMN-IRB and are willing to avoid oat consumption and rigorous physical activity
the day prior to and through test and to consume a low-polyphenol diet for 1 week prior to
the study. The foods rich in polyphenols include all berries, apples, pears, citrus fruits,
fruit juices, onions, chocolate, wine, coffee, tea, beans, nuts, soy products and most
spices
Exclusion Criteria:
1. Presence of GI conditions that interfere with absorption;
2. Clinically significant endocrine, cardiovascular, pulmonary, renal, hepatic,
pancreatic, biliary or neurologic disorders;
3. Major trauma or surgery within 3 months of visit;
4. Cancer in the prior 2 years;
5. Allergic to oat products;
6. Women who are pregnant or lactating;
7. Smoking;
8. Drinking alcohol >5 drinks/week;
9. Using nutraceuticals;
10. Blood pressure medication;
11. NSAID (>800 mg ibuprofen/week)
12. Vitamin supplementation
13. Anticoagulants or hypoglycemic drugs
14. Oat products consumption and rigorous physical activity the day before the test and
consumption of a high-polyphenol diet in week prior to the test.
15. Moderate-intensity cardiorespiratory exercise training for =30 min•d-1 on =5 d•wk-1
for a total of =150 min•wk-1, vigorous-intensity cardiorespiratory exercise training
for =20 min•d-1 on =3 d•wk-1 (=75 min•wk-1), or a combination of moderate- and
vigorous-intensity exercise to achieve a total energy expenditure of =500-1000
MET•min•wk-1
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