Transcranial Magnetic Stimulation for Evaluation and Treatment of Repetetive Behaviors in Autism

Autism Clinical Trial

Official title: Repetetive Transcranial Magnetic Stimulation for Evaluation and Treatment of Repetetive Behavior in Subjects With Autism Spectrum Disorders.

Status Terminated

Clinical Trial Summary

This study is a trial of low frequency Repetitive Transcranial magnetic stimulation( rTMS) for subjects with autism spectrum disorders, specially targeting repetitive behaviors.

Clinical Trial Description

This project is a 3-week double blind cross-over trial for adolescents and adults who meet criteria for autism and have clinically prominent repetitive behaviors. The investigator will apply low frequency rTMS for 20 minutes 5 times a week for 3 weeks targeting the area of brain which was involved in repetitive behaviors. The investigator will obtain clinical measures of repetitive behaviors as well as social functioning pre and post treatment. As a control and a cross-over condition , we will stimulate other area of brain which has nothing to do with repetitive behaviors but may improve social functioning in autism spectrum disorders. In addition to r TMS we will perform a pre and post treatment perfusion functional MRI and obtain TMS measure of excitability of brain. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Asperger Disorder
• Asperger Syndrome
• Autism
• Autistic Disorder
• Disease
• Other Developmental Pervasive Disorder.

• NCT number: NCT01983189
• Study type: Interventional
• Source: New York State Psychiatric Institute
• Status: Terminated
• Phase: Phase 2
• Start date: November 2008
• Completion date: November 2010