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Autism clinical trials

View clinical trials related to Autism.

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NCT ID: NCT00208559 Completed - Autism Clinical Trials

Ziprasidone in Children With Autism: A Pilot Study

Start date: February 2002
Phase: Phase 2
Study type: Interventional

The purpose of this study is to see if the drug, ziprasidone, is effective in treating problems in adolescent associated with autism.

NCT ID: NCT00208533 Completed - Autism Clinical Trials

Aripiprazole in Children With Autism: A Pilot Study

Start date: February 2004
Phase: Phase 2
Study type: Interventional

This is a 6-week open pilot study of aripiprazole for the treatment of adolescents, aged 12 to 18 years, diagnosed with autism. Children who qualify for the study will be treated with aripiprazole for 6 weeks. Treatment is provided at no cost.

NCT ID: NCT00183404 Completed - Autism Clinical Trials

Long-Term Olanzapine Treatment in Children With Autism

Start date: September 2004
Phase: Phase 2/Phase 3
Study type: Interventional

This study will determine the short- and long-term safety and effectiveness of the drug olanzapine (Zyprexa®) for reducing symptoms of autism in children.

NCT ID: NCT00178503 Completed - Autism Clinical Trials

Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children

Start date: September 2005
Phase: Phase 2/Phase 3
Study type: Interventional

This study examined the cognitive and behavioral differences in children who have an autism spectrum disorder (ASD) with or without additional symptoms of ADHD. The study also examined the effectiveness of a range of doses of methylphenidate in improving cognitive and behavioral outcomes in children with both ASD and ADHD.

NCT ID: NCT00166621 Completed - Autism Clinical Trials

Early Pharmacotherapy Aimed at Neuroplasticity in Autism : Safety and Efficacy

Start date: March 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy, safety, and population pharmacokinetics and determinants of drug responses to buspirone in children with autism using a randomized, double blind, cross over study in children ages 2 to 6 years.

NCT ID: NCT00161135 Completed - Autism Clinical Trials

Magnetic Resonance Imaging in Children and Adolescents With Autism and Multiple Complex Developmental Disorders

Start date: January 1999
Phase: N/A
Study type: Observational

This study aims to investigate the overlap and differences between autism and MCDD as neuropsychiatric childhood disorders. MRI scans are acquired from subjects with autism, subjects with a diagnosis of MCDD and typically developing controls. Volumetric measure of various brain regions are compared between groups. We hypothesize that subjects with autism will have larger brains than controls, whereas subjects with MCDD will have smaller brains.

NCT ID: NCT00156221 Completed - Autism Clinical Trials

MR Scanning of Very Young Children With Severe Developmental Disorders

Start date: September 2000
Phase: N/A
Study type: Observational

The specific is to study the MR morphologic and spectroscopic brain correlates and predictors of development in children with severe developmental disorders (autistic spectrum disorders and/or mental retardation and/or language disorders). Given the frequently observed association of autism with known medical conditions, particularly in cases with comorbid mental retardation and in cases with atypical autism (Rutter et al., 1994; Gillberg, 1995), children with suspected autism or related developmental disorders will be asked to participate in an extensive state of the art laboratory work-up which includes T1 and T2 weighted MRI of the brain. MRI data will be analyzed both qualitatively, looking for focal abnormalities and degree of myelination, and quantitatively, measuring volumes of total brain, cerebellum, ventricles and grey and white matter. For research purposes, the work-up will be supplied with proton Magnetic Resonance Spectroscopy (MRS) of the brain. This data set provides the opportunity to chart brain-behavior relationships in young children with suspected autism and related PDD cross-sectionally.

NCT ID: NCT00110708 Active, not recruiting - Autism Clinical Trials

Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism

Start date: April 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if human immunoglobulin given by mouth twice a day is effective in treating the persistent gastrointestinal (GI) problems such as diarrhea, constipation, abdominal pain, and bloating, in children with autism.

NCT ID: NCT00106652 Completed - Autism Clinical Trials

Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)

Start date: September 2001
Phase: N/A
Study type: Observational

The purpose of this study is to understand how genes, environment, and the interplay between the two, influences the development of autism and other neurodevelopmental disorders.

NCT ID: NCT00106210 Completed - Autism Clinical Trials

School- and Home-Based Early Intervention for Toddlers With Autism

Start date: May 2003
Phase: N/A
Study type: Interventional

This study will determine the impact of early intervention on the communication and social development of toddlers with autism.