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Atrophy clinical trials

View clinical trials related to Atrophy.

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NCT ID: NCT02244671 Completed - Orbital Atrophy Clinical Trials

Botulinum-assisted Orbital Fat Augmentation With PRP (Platelet-rich-plasma)

Start date: January 2014
Phase: N/A
Study type: Interventional

immobilization of yoked extra-ocular muscles in the anophthalmic orbit, in conjunction with platelet-rich-plasma, will improve integration of viable adipocytes injected into orbital fat

NCT ID: NCT02227823 Completed - Clinical trials for Spinal Muscular Atrophy Type 3

Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3

EMOTAS
Start date: July 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate safety and efficacy of anti-cholinesterase therapy on the motor function in SMA type 3 patients with impaired neuromuscular junction (NMJ).

NCT ID: NCT02195986 Completed - Atrophic Vaginitis Clinical Trials

A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis

Start date: June 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the therapeutic equivalence of Mylan's estradiol vaginal cream to Estrace® cream and superiority of both products to placebo. The protocol describes a randomized, double-blind, multi-dose, placebo-controlled, parallel study of a 7 day treatment.

NCT ID: NCT02185677 Completed - Clinical trials for Multiple System Atrophy

Cognitive and Behavioral Dysexecutive Syndrome in Multiple System Atrophy

CogAMS
Start date: May 14, 2014
Phase:
Study type: Observational

The main objective of the study is to compare the score to the Behavioral Dysexecutive Syndrome Inventory (BDSI) between Parkinsonian Multiple system Atrophy MSA-P patients and cerebellar Multiple System Atrophy (MSA-C) patients matched on disease duration, age (± 7 years) and sex .

NCT ID: NCT02156141 Completed - Healthy Subjects Clinical Trials

High Intensity Training in Patients With Spinal and Bulbar Muscular Atrophy

HIT in Kennedy
Start date: June 2014
Phase: N/A
Study type: Interventional

We want investigate if high intensity training can increase daily functionality without causing muscle damage in patients Spinal and Bulbar Muscular Atrophy . We want to study if there is a difference in effect with supervised and unsupervised training. Furthermore we want to study if a supervised training program will motivate participants to continue training by the end of the program.

NCT ID: NCT02155764 Completed - Tooth Extraction Clinical Trials

Ridge Preservation With New Class of Osteoplastic Materials

RP
Start date: September 1, 2016
Phase: Phase 2
Study type: Interventional

Return to normal life and shortening rehabilitation period of patients after surgical removal of teeth is important and urgent social problem. In this regard, higher demands for quality of care and treatment of patients, which requires the development of new approaches to the treatment of patients, the introduction of new technologies and the associated development of new materials . Serious problem of contemporary oral and maxillo-facial surgery and dentistry is augmentation of bone defects generated during the surgical treatment of diseases and injuries of the bones. The results of surgical repair of bone defects are more dependent on the course of the process of reparative osteogenesis. Long-term periods of clinical studies indicate that reparative osteogenesis in posttraumatic bone defects is slow - months and years, and in some cases no bone defects filled with bone tissue. This project aims at addressing the preservation of bone volume in humans after tooth extraction using biomaterials with optimum performance. The practical significance of the project is to establish an effective tissue response and, thus, possible subsequent quality installation of dental implants. The proposed solution is based on the scientific development of the operative techniques, and a comparative analysis of several classes of biomaterials (xenogenic and synthetic analogs), including the use of biological precursors of bone apatite mineralization having osteoinductive (stimulating) properties.

NCT ID: NCT02152761 Completed - Clinical trials for Muscle Wasting (Atrophy) After Hip Fracture Surgery

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

Start date: September 16, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study was to assess if bimagrumab is safe and effective in patients with muscle wasting (atrophy) after hip fracture surgery.

NCT ID: NCT02148887 Completed - Clinical trials for Investigating Spinal Atrophy in Patients With Spinal Injury

Plasticity of Grey and White Matter in Response to Motor Skill Training in Healthy Individuals and Those With Spinal Cord Injury

Start date: February 2014
Phase:
Study type: Observational

We aim to investigate the effect of motor skill training of the upper and lower limbs on the function and structure of the CNS as measured by neuroimaging parameters sensitive to changes in tissue volume and density and the properties of myelin.

NCT ID: NCT02145364 Completed - Acne Scars Clinical Trials

Ultherapy® for the Treatment of Acne Scars

Start date: May 2014
Phase: N/A
Study type: Interventional

This is a prospective, multi-site trial to be conducted at 2 clinical sites. Up to 20 subjects will receive study treatments. Following study treatments, follow-up visits will occur at 60, 90 and 180 days from each subject's last study treatment.

NCT ID: NCT02144987 Completed - Asherman's Syndrome Clinical Trials

Bone Marrow Stem Cell Treatment for Asherman's Syndrome and Endometrial Atrophy

BMSCT
Start date: April 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Bone Marrow Stem Cell transplantation may improve Assisted Reproduction Techniques (ART) outcomes in refractive Asherman's Syndrome or Atrophic Endometrium.