Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars

Atrophic Acne Scar Clinical Trial

— PRP  

Official title:

Fractional CO2 Laser Combined With Platelet Rich Plasma Fluid Versus Gel Form in Treatment of Atrophic Acne Scars: A Randomized Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04580758
• Other study ID #: Kasr El Aini Hospital
• Status: Recruiting
• Phase: Early Phase 1
• Start date: February 25, 2020
• Est. completion date: January 31, 2021

Study information

• Verified date: September 2020
• Source: Kasr El Aini Hospital
• Contact: Heba A Abd El Kader, MD
• Phone: 01142479792
• Email: H_abdelkader2007[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars

Description:

The study will include 20 patients, treated with fractional CO2 laser plus PRP fluid on one side of the face and fractional CO2 laser plus PRP gel on the other side.

Choosing which side of the face will be injected with PRP fluid and which side will be injected with PRP gel will be chosen according to a randomization table for each patient.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 20
• Est. completion date: January 31, 2021
• Est. primary completion date: December 31, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age above 18

• Both genders

• Skin types III - V

• Willingness and ability to comply with the requirements of the protocol

• Atrophic acne scars

Exclusion Criteria:

• Patients with active acne

• Patients with herpes labialis, bacterial infections, other infections such as HBV. HCV or HIV.

• Oral isotretinoin use in the previous 6 months

• Pregnancy

• Tendency to keloid formation

• Patients with severe systemic illness or malignancy

• Patients with connective tissue diseases

• Patients with bleeding tendencies or any other hematological disease

Related Conditions & MeSH terms

• Atrophic Acne Scar
• Atrophy

Intervention

Combination Product:
• Fractional laser with PRP fluid or PRP gel
20 participants divided into 2 groups of 10 10 participants will do Fractional laser with PRP fluid sessions and 10 participants will do Fractional laser with PRP gel

Locations

Country	Name	City	State
Egypt	Kasr Al Ainy Hospital	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Yasmine Ahmed Abd El-Maguid El-Hadidy

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Test which combination is more effective, fractional laser with PRP fluid or fractional laser with PRP gel	Effectiveness of each combination will be measured with OCT, depth of a fixed scar on each side of the face will be measured at baseline and then compared with 1 month after the last session and 3 months after the last session	one year