NCT06319768 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Alves R, Grimalt R
Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review. Dermatol Ther (Heidelb). 2020 Aug;10(4):623-633. doi: 10.1007/s13555-020-00408-5. Epub 2020 Jun 17.
Balazic E, Axler E, Konisky H, Khanna U, Kobets K
Pentoxifylline in dermatology. J Cosmet Dermatol. 2023 Feb;22(2):410-417. doi: 10.1111/jocd.15445. Epub 2022 Oct 31.
Bhargava S, Kroumpouzos G, Varma K, Kumar U
Combination therapy using subcision, needling, and platelet-rich plasma in the management of grade 4 atrophic acne scars: A pilot study. J Cosmet Dermatol. 2019 Aug;18(4):1092-1097. doi: 10.1111/jocd.12935. Epub 2019 Mar 28.
Connolly D, Vu HL, Mariwalla K, Saedi N
Acne Scarring-Pathogenesis, Evaluation, and Treatment Options. J Clin Aesthet Dermatol. 2017 Sep;10(9):12-23. Epub 2017 Sep 1.

Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined

Clinical trial NCT06319768 - References