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Clinical Trial Summary

In this study a new technique for ablation in atrioventricular nodal reentrant tachycardia using cryo-energy will be studied in cases where the standard approach has higher risk.


Clinical Trial Description

Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common cause of fast heartbeats in young people. People with AVNRT have two pathways within the heart, the fast pathway (FP) and slow pathway (SP). A treatment for AVNRT is ablation (burning or freezing) of the SP. This can be done with either radiofrequency or cryo-energy. A complication which occurs in 1% of cases is AV block (AVB), meaning the person needs a pacemaker.

Slow pathway ablation is a problem in people when the electrocardiogram (ECG) shows a long PR interval, with greater rates of AVB. This accounts for 5% of AVNRT cases. A possible solution is to treat the FP with cryo-energy and leave the SP intact. This pilot study aims to show this is safe and effective. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04122807
Study type Interventional
Source Lawson Health Research Institute
Contact Matthew K Rowe, MBBS
Phone 1-519-663-3746
Email matthew.rowe@lhsc.on.ca
Status Recruiting
Phase Early Phase 1
Start date November 2019
Completion date December 2021