Ethnic Differences in Mechanisms of Action of Dupilumab

Status Recruiting

Clinical Trial Summary

Previous research has shown that Asian and African Americans are more likely to develop atopic dermatitis (AD) than their Caucasian counterparts. However, limited information is known about AD in Asian and African American populations because most molecular studies have focused on Caucasians with AD. This trial will determine differences in inflammatory responses to dupilumab between Caucasian, Asian, and African American patients with AD. The central hypothesis of this study is that ethnic differences in both immune and stromal cells contribute to variability in AD presentation and response to anti-interleukin-4 receptor (IL-4R) inhibition with dupilumab.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05268107
Study type	Interventional
Source	University of Michigan
Contact	Nicole Nechiporchik
Phone	734-936-7519
Email	nnechipo@med.umich.edu
Status	Recruiting
Phase	Phase 4
Start date	January 25, 2023
Completion date	June 2025

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See also
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