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Study of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis

Atopic Dermatitis Clinical Trial

Official title:
A Phase 2a, Multicenter, Randomized, Double-blind, Vehicle-controlled, Parallel-group Study to Determine the Safety, Tolerability, Pharmacokinetics and Efficacy of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis

Clinical Trial Summary

This is a first-in-human, randomized, double-blind, parallel-group, vehicle-controlled study to evaluate the efficacy, safety, tolerability, and PK of ATI-1777 solution following twice-daily applications to target areas of participants with moderate or severe atopic dermatitis (AD).

Clinical Trial Description

Participants underwent screening evaluations to determine eligibility up to 30 days prior to randomization. Participants who meet all the entry criteria were randomized on Day 1 to active or vehicle treatment. Participants applied study drug (ATI-1777 topical solution 2.0% w/w or vehicle) twice daily for 4 weeks with weekly study visits and were to return 2 weeks after the last dose of study medication for a Post treatment Follow-up (PTFU) Visit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04598269
Study type Interventional
Source Aclaris Therapeutics, Inc.
Contact
Status Completed
Phase Phase 2
Start date September 30, 2020
Completion date April 22, 2021
View Details
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