Evaluating Skin Barrier Dysfunction in Infants at High Risk of Atopy

Status Withdrawn

Clinical Trial Summary

It is hypothesized that food allergy is preceded by atopic dermatitis (AD), due to a disruption of skin barrier which can predispose one to food sensitization through the skin. The central hypothesis is that increased transepidermal water loss (TEWL) assessment and skin tape strip analysis (STS) of lipid and filaggrin breakdown products will be predictive markers for the development of AD. Additionally, the associated changes in TEWL and STS will further improve the identification of infants at risk of early food sensitization, compared to family history alone.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03089476
Study type	Interventional
Source	National Jewish Health
Contact
Status	Withdrawn
Phase	N/A
Start date	September 30, 2017
Completion date	July 30, 2018

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See also
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