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Atopic Dermatitis clinical trials

View clinical trials related to Atopic Dermatitis.

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NCT ID: NCT03676036 Completed - Atopic Dermatitis Clinical Trials

Efficacy and Steroid Sparing Potential Study of DGLA Cream in Patients With Moderate to Severe Atopic Dermatitis

Start date: June 2015
Phase: Phase 2
Study type: Interventional

This study will investigate the steroid sparing potential of DS107E to vehicle in patients with moderate to severe atopic dermatitis. DS107E or vehicle will be topically administered with a steroid twice a day for the first 7 days. For the following 28 days DS107E or vehicle will be topically administered twice a day. This study will enrol approximately 40 adult patients.

NCT ID: NCT03667014 Completed - Atopic Dermatitis Clinical Trials

The Impact of Dupilumab on Quality of Life in Moderate to Severe Atopic Dermatitis Patients

Start date: November 1, 2018
Phase: Phase 4
Study type: Interventional

This is a single-arm, open-label study, which will examine the effect of dupilumab on quality of life in atopic dermatitis patients.

NCT ID: NCT03661138 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate Safety of Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

Rising Up
Start date: October 27, 2018
Phase: Phase 3
Study type: Interventional

The objective of this study is to assess the safety of upadacitinib combined with topical corticosteroids (TCS) in adolescent and adult participants in Japan with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.

NCT ID: NCT03645057 Completed - Atopic Dermatitis Clinical Trials

ASPIRE: PROs & Caregiver Burden in Children With Atopic Dermatitis

Start date: February 20, 2019
Phase: Phase 3
Study type: Interventional

This is an open-label, randomized, cross-sectional study to monitor the effects of crisaborole and tacrolimus 0.03% on patient-reported outcomes and caregiver burden in children (ages 2 to 15 years, inclusive) with ≤ moderate atopic dermatitis over a 12 week period of time. The goal of this study is to detect changes in PROs and caregiver burden during treatment for atopic dermatitis of moderate or less severity. The study design will allow us to correlate PROs and caregiver burden with treatment response and disease improvement in children.

NCT ID: NCT03632174 Completed - Atopic Dermatitis Clinical Trials

Evaluation and Comparison of 2 Cosmetic Investigational Products in Adults With Atopic Dermatitis

Start date: January 21, 2019
Phase: N/A
Study type: Interventional

The study consists in the application of 2 investigational products (one group per investigational product) under normal conditions of use, in adult participants with Atopic Dermatitis. It is carried out on cosmetic products, with the aim to further confirm safety of these products

NCT ID: NCT03622463 Completed - Atopic Dermatitis Clinical Trials

A Trial of Antroquinonol in Patients With Atopic Dermatitis

Start date: July 17, 2018
Phase: Phase 2
Study type: Interventional

This is a multi-centers, phase IIa, double blind, randomized, placebo-controlled trial of Antroquinonol in patients with atopic dermatitis.Duration of treatment is 12 week in total. Study visits will occur every 4 weeks. AEs/SAEs, changes to concomitant medications will be noted, vital signs will be taken, and efficacy evaluations will be performed as well. The last estimation of variable scores will occur for all subjects.

NCT ID: NCT03619161 Completed - Atopic Dermatitis Clinical Trials

Bleach vs. Bubbles: Assessing the Impact of the Bathroom Environment on Eczema

Start date: June 21, 2018
Phase: N/A
Study type: Interventional

Purpose: Evaluate the impact of cleaning the bathroom environment on the severity of eczema. Determine if part of the efficacy of bleach baths may be in cleaning the bathroom. Record data on the process in order to improve future interventions. Participants: Patients and families with eczema Procedures (methods): - Obtain baseline eczema severity scores and bacterial cultures from bathtubs - Randomize subjects to receive (1) a bathtub culture alone; (2) a culture and bathroom cleaning; and (3) a culture, cleaning, and bleach baths. - Measure changes in eczema severity scores over 4 weeks - Qualitatively evaluate the process by participants and investigators

NCT ID: NCT03614221 Completed - Atopic Dermatitis Clinical Trials

Comparison of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® Ointment 0.1% in Treating Atopic Dermatitis

Start date: June 3, 2019
Phase: Phase 2
Study type: Interventional

The aims of this study are: 1. Compare the efficacy of Lindioil ointment and Protopic® ointment in treating atopic dermatitis. 2. Compare the safety of Lindioil ointment and Protopic® ointment in treating atopic dermatitis. 3. Compare the time to relapse after ceasing of treatment of Lindioil ointment and Protopic® ointment. 4. Compare the change of skin microbiome before and after Lindioil ointment and Protopic® ointment treatment.

NCT ID: NCT03610386 Completed - Atopic Dermatitis Clinical Trials

Effects of an Anti-TRPM8 in the Atopic Dermatitis Pruritus

DA-TRPM8
Start date: November 21, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to analyse the effect of the menthoxypropanediol, a derivative of menthol, on the pruritus of atopic dermatitis (ex vivo study).

NCT ID: NCT03585296 Completed - Atopic Dermatitis Clinical Trials

A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis

Start date: July 10, 2018
Phase: Phase 2
Study type: Interventional

This is an open label, multicenter study designed to evaluate the safety and tolerability of ATI-502 Topical Solution in male and female subjects with moderate or severe atopic dermatitis (AD). Subjects will be required to apply ATI-502 study medication to their identified AD treatment areas. All subjects will be required to complete a safety follow up visit 4 weeks post last study medication application