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Atopic Dermatitis clinical trials

View clinical trials related to Atopic Dermatitis.

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NCT ID: NCT04040192 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate Long-Term Maintenance Treatment With Once Daily Crisaborole Ointment 2% in Pediatric and Adult Participants With Mild-to-Moderate Atopic Dermatitis

Start date: September 12, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate crisaborole therapy once daily (QD) as a long-term topical maintenance therapy for the reduction of flare in responders to crisaborole twice daily (BID) treatment.

NCT ID: NCT04033367 Completed - Atopic Dermatitis Clinical Trials

SAR231893-LPS15497- "Dupilumab Effect on Sleep in AD Patients"

Start date: August 22, 2019
Phase: Phase 4
Study type: Interventional

Primary Objective: To evaluate the effect of dupilumab on sleep quality in adult participants with moderate to severe atopic dermatitis (AD). Secondary Objectives: To evaluate the effect of dupilumab on objective and subjective quantitative sleep parameters, AD related outcomes, and daytime consequences of sleep deprivation. To continue to assess the safety and tolerability throughout the study.

NCT ID: NCT04023084 Completed - Atopic Dermatitis Clinical Trials

Response of Children With Atopic Dermatitis (Eczema) to Eucrisa

Start date: October 3, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to develop biomarkers to predict what medication is best for each child with atopic dermatitis (eczema). Participants will come in to Lurie Children's Allergy of Dermatology clinic for a skin examination and complete surveys. They will apply Eucrisa medication to their skin for 28 days before returning for a second and final skin examination and complete surveys. During these skin exams, tape will be placed on the skin and removed to collect skin cell samples. Photos will also be taken of the skin where tape was placed. There is an optional blood draw.

NCT ID: NCT04021862 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate the Safety and Efficacy of Bermekimab in Patients With Moderate to Severe Atopic Dermatitis

Start date: October 16, 2019
Phase: Phase 2
Study type: Interventional

A Study to Evaluate the Safety and Efficacy of Bermekimab in Patients With Moderate to Severe Atopic Dermatitis

NCT ID: NCT04018027 Completed - Atopic Dermatitis Clinical Trials

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

KARE
Start date: June 29, 2019
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, 4-arm, placebo-controlled study to evaluate the efficacy and safety of twice-daily (BID) oral difelikefalin (CR845) in adult subjects with atopic dermatitis (AD) and moderate to severe pruritus.

NCT ID: NCT04008784 Completed - Atopic Dermatitis Clinical Trials

Improvement of Short Term Outcome of Mild to Moderate Atopic Dermatitis Using a Combination of Crisaborole and a Concomitant Topical Corticosteroid Over a 8 Week Period

Start date: September 16, 2019
Phase:
Study type: Observational

This trial is a single-center two arm, open label observational prospective study, that will evaluate the safety and efficacy of crisaborole ointment, 2% alone compared to a combination therapy of crisaborole and a topical corticosteroid (Triamcinolone Acetonide Ointment, 0.1%) over a 8 week period for the treatment of mild to moderate atopic dermatitis.

NCT ID: NCT03961529 Completed - Atopic Dermatitis Clinical Trials

Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopic Dermatitis

Start date: May 14, 2019
Phase: Phase 3
Study type: Interventional

To demonstrate the safety of 1% OPA-15406 ointment in adult patients with AD and of 0.3% and 1% OPA-15406 ointments in pediatric patients with AD administered twice daily for 52 weeks.

NCT ID: NCT03954158 Completed - Atopic Dermatitis Clinical Trials

Study to Assess Efficacy and Safety of Two Regimens of Crisaborole Ointment 2% in Japanese Participants Aged ≥2 Years With Mild to Moderate Atopic Dermatitis

Start date: June 15, 2019
Phase: Phase 2
Study type: Interventional

This is a Phase 2b, multi-center, randomized, double-blind, vehicle-controlled, intraparticipant study to evaluate efficacy and safety of two regimens of crisaborole ointment 2% in Japanese pediatric and adult participants (cohort 1: 12 years and older, cohort 2: 2 to under 12 years old) with mild to moderate Atopic Dermatitis (AD).

NCT ID: NCT03921411 Completed - Atopic Dermatitis Clinical Trials

A Pharmacokinetics and Safety Study of Nemolizumab in Adolescent Participants With Atopic Dermatitis (AD)

Start date: April 9, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study was to evaluate the pharmacokinetics and safety of nemolizumab in adolescent participants with AD.

NCT ID: NCT03920852 Completed - Atopic Dermatitis Clinical Trials

A Maximum Use Trial of Ruxolitinib Cream in Adolescent and Adult Participants With Atopic Dermatitis

Start date: May 30, 2019
Phase: Phase 1
Study type: Interventional

This is an open-label maximum use trial to evaluate ruxolitinib safety and blood levels after its topical application twice daily to affected areas (≥ 25% BSA) in adolescent and adult participants with atopic dermatitis (AD) and to determine if its systemic bioavailability results in any adverse events.