Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study

Atelectasis Clinical Trial

— ATELHO  

Official title:

Perioperative Atelectasis in Patients Undergoing Orthopaedic Surgery: Prospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05384795
• Other study ID #: CER-VD 2022-00712
• Status: Completed
• Start date: May 16, 2022
• Est. completion date: December 31, 2022

Study information

• Verified date: April 2023
• Source: Centre Hospitalier Universitaire Vaudois
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Description:

Atelectasis is one of the most common pulmonary complications in the perioperative period, occurring in 85% to 90% of patients under general anesthesia. It can be responsible for hypoxemia and be associated with postoperative pulmonary complications such as pneumonia. The consequences are a prolongation of the hospital stay and an increase in mortality.

The appearance of perioperative atelectasis is mainly secondary to the induction of general anesthesia with an incidence up to 90%. The different causes are, for example, the administration of muscle relaxants, mechanical ventilation and the position of the patient.

In orthopedic surgery, many procedures are performed under spinal anesthesia or under peripheral nerve block. At present, there are no studies measuring the incidence of atelectasis in patients operated under these two techniques of locoregional anesthesia, with the exception of parturients undergoing cesarean section.

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 141
• Est. completion date: December 31, 2022
• Est. primary completion date: December 31, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients over the age of 18;

• Patients scheduled for an elective operation at the Orthopedic Hospital of CHUV;

• Signature of the study consent

Exclusion Criteria:

• Thoracic deformities preventing the performance of pulmonary ultrasound (dressings, drains, fractures, etc.);

• Refusal to participate;

• Patient does not speak French.

• Inability to discern

Related Conditions & MeSH terms

• Atelectasis
• Pulmonary Atelectasis

Intervention

Other:
• Lung ultrasound
Lung atelectasis score

Locations

Country	Name	City	State
Switzerland	Centre Hospitalier Universitaire Vaudois	Lausanne	Vaud

Sponsors (1)

Lead Sponsor	Collaborator
Eric Albrecht

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lung atelectasis score	Atelectasis score based on validated ultrasound quantification (comparing different anesthesia techniques)	immediately after the surgery
Secondary	Lung atelectasis score	Atelectasis score	Four timepoints: at baseline, immediatly before surgery (after anesthesia induction), immediately after the surgery, and at the recovery room