Arthroplasty Clinical Trial
Official title:
The Efficacy and Optimal Dose of Sufentanil in Patient Controlled Analgesia After Moderate Surgery
Verified date | July 2015 |
Source | Second Affiliated Hospital of Xi'an Jiaotong University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Effective postoperative pain control is essential for patients and inadequate postoperative pain relief can cause mental and psychological sufferings. Despite the growing concern on postoperative pain management, acute postoperative pain is still poorly managed. Though numerous clinical practice guidelines for postoperative pain management have been published throughout the last decades, inadequate pain relief remain a big health care issue. Sufentanil has been used as satisfied pain control drug because of its strong potency of analgesia for a long while. But its use in patient controlled intravenous analgesia (PCIA) has not been clarified. And the dilemma of safety concern and insufficient dosage of analgesic is a common problem. Thus the investigators design this prospective randomized controlled double blinded trial to observe the efficacy and the optimal dose of sufentanil in PCIA in patients underwent moderate surgery for the purpose of providing reference in clinical practice.
Status | Unknown status |
Enrollment | 60 |
Est. completion date | |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 75 Years |
Eligibility |
Inclusion Criteria: - 20 to 75 years old, - BMI 18 to 28kg/m2, - ASA I to II grade, - anticipated surgery duration within 4hrs, - agree to sign consent paper. Exclusion Criteria: - severe respiratory, - cardiovascular or neurological disease, - hepatic or renal dysfunction, - psychiatric history or with unstable mental state, - drug addiction or dependence |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital of Xi'an Jiaotong University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change of Pain on the VAS scale after surgery | 2, 6, 24 and 48hrs after surgery | ||
Primary | Change of Pain on the NRS scale after surgery | 2, 6, 24 and 48hrs after surgery |
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