Clinical Trials Logo

Clinical Trial Summary

Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02100579
Study type Interventional
Source Northwestern University
Contact Mark Kendall, MD
Phone 312-695-2528
Email m-kendall@northwestern.edu
Status Recruiting
Phase Phase 4
Start date March 2014

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05666479 - CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
Recruiting NCT05002387 - Diagnostic Knee Needle Arthroscopy in Predicting Unicompartmental Knee Osteoarthritis N/A
Recruiting NCT06080763 - Biomechanics and Clinical Outcomes in Responders and Non-Responders
Completed NCT03008967 - A Study of Patients Undergoing Total Knee and Hip Arthroplasty at a Regional Hospital in Denmark N/A
Withdrawn NCT02255877 - ZIPS Study - Zip Incision Approximation vs. STAPLE Phase 4
Completed NCT02642731 - Kidney Biomarkers of Acute Kidney Injury in Patients With Knee Arthroplasty N/A
Completed NCT02525588 - Polyethylene Wear Study on the Triathlon Total Knee Prosthesis N/A
Completed NCT01799772 - The Feasibility of a Comprehensive Behavioral Intervention in Patient Post TKA Phase 1/Phase 2
Completed NCT02520531 - Scorpio Posterior Stabilised (PS) vs Scorpio NRG ("Energize") PS - Total Knee Arthroplasty N/A
Completed NCT03183856 - Comparison of Ambulatory and Functional Improvement by Morning Walk N/A
Completed NCT03569397 - Music Therapy Versus Control for Total Knee Arthroplasty N/A
Terminated NCT02711592 - Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study N/A
Completed NCT03145493 - Effect of Suction Drains in Total Knee Arthroplasty With Tranexamic Acid N/A
Terminated NCT05602701 - Preoperative Prediction of Postoperative Physical Function
Recruiting NCT03570944 - Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol (POWER2)
Withdrawn NCT02553122 - The Combined Efficacy of Evicel and Tranexamic Acid on Total Knee Arthroplasty Phase 3
Completed NCT02773537 - Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial N/A
Recruiting NCT02385383 - An Intravenous Iron Based Protocol for Preoperative Anaemia in Hip and Knee Surgery - An Observational Study N/A
Completed NCT02121392 - Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty N/A
Terminated NCT02155712 - Triathlon Tritanium Knee Outcomes Study N/A