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Arthritis clinical trials

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NCT ID: NCT00655824 Terminated - Clinical trials for Arthritis, Rheumatoid

Long-term Efficacy and Safety of Repeated Ofatumumab Treatment Courses in RA Patients Who Previously Received Ofatumumab or Placebo in Trial Hx-CD20-403

Start date: January 1, 2008
Phase: Phase 2
Study type: Interventional

A 3-year open-label trial for patients who previously participated in Trial Hx-CD20-403 and who fulfill the eligibility criteria for this trial (GEN413) . Th e primary purpose of the trial is to evaluate the long-term effectiveness of repeated courses ( a maximum of 9 treatment courses) of ofatumumab in RA patients who previously received ofatumumab or placebo in Trial Hx-CD20-403.

NCT ID: NCT00637780 Terminated - Clinical trials for Arthritis, Juvenile Rheumatoid

Study To Determine The Pharmacokinetics Of Sulfasalazine In Children With Juvenile Idiopathic Arthritis

Start date: June 2010
Phase: Phase 4
Study type: Interventional

This study will characterize the steady state pharmacokinetics of sulfasalazine delayed release tablets in pediatric Juvenile Idiopathic Arthritis patients. Data from this study will fulfill the post approval commitment to the FDA.

NCT ID: NCT00634933 Terminated - Clinical trials for Arthritis, Rheumatoid

Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis

Start date: March 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of two dosing regimens of a compound known as TRU-015 in combination with methotrexate (MTX) in patients with active rheumatoid arthritis.

NCT ID: NCT00611455 Terminated - Clinical trials for Arthritis, Rheumatoid

Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to MTX Therapy

Start date: January 1, 2008
Phase: Phase 3
Study type: Interventional

This is a phase III, double-blind, randomized, multicenter, and parallel group trial with a duration of 24 weeks, followed by a 120 week Open-label Period. the primary purpose of the study is to demonstrate the efficacy of ofatumumab in reducing clinical signs and symptoms in adult RA patients after a single course of ofatumumab.

NCT ID: NCT00603525 Terminated - Clinical trials for Arthritis, Rheumatoid

Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to TNF-α Antagonist Therapy

Start date: January 2008
Phase: Phase 3
Study type: Interventional

This is a phase III, double-blind, randomized, multicenter, and parallel group trial with a duration of 24 weeks, followed by a 120 week Open-label Period. The primary purpose of the study is to demonstrate the efficacy and safety of ofatumumab in reducing clinical signs and symptoms in adult RA patients who had an inadequate response to TNF-α antagonist therapy.

NCT ID: NCT00588887 Terminated - Clinical trials for Rheumatoid Arthritis

Total Knee Replacement With Duracon® and Vanguard™ Prostheses

Start date: June 2005
Phase: N/A
Study type: Observational

The purpose of this study is to compare range of motion, Knee Society Scores, and duration of surgery for different total knee prostheses.

NCT ID: NCT00588783 Terminated - Clinical trials for Rheumatoid Arthritis

I-beam and Cruciate Tibial Components Used in Total Knee Replacement

Start date: August 2006
Phase: N/A
Study type: Observational

The purpose of this study is to compare the clinical outcomes of using an I-beam or cruciate tibial component in total knee replacement.

NCT ID: NCT00583557 Terminated - Clinical trials for Rheumatoid Arthritis

A Continuation Trial for Subjects With Rheumatoid Arthritis That Have Completed Protocol LBRA01

Start date: January 2005
Phase: Phase 2
Study type: Interventional

This is a continuation trial of LymphoStat-B™ to evaluate the long-term safety in subjects with Rheumatoid Arthritis that completed study LBRA01 and benefitted from treatment.

NCT ID: NCT00579059 Terminated - Clinical trials for Rheumatoid Arthritis

Maxim® Knee Pop-Top® Tibia vs. Regular Maxim® Knee Tibia

Start date: May 2004
Phase: N/A
Study type: Interventional

The purpose of this prospective clinical data collection is to compare the outcomes of two different tibial bearings: the Maxim® Pop-Top® Tibia and Maxim® Modular Tibia.

NCT ID: NCT00537667 Terminated - Clinical trials for Rheumatoid Arthritis

The SPECTRA Study

Start date: August 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare IL-1ra and the combination of IL-1ra and PEGsTNF-RI with respect to their ability to reduce inflammation and bone and cartilage destruction in the synovium of subjects with rheumatoid arthritis.