ARDS Clinical Trial - Prone Positioning in COVID-19 Patients

Status Recruiting

Clinical Trial Summary

Prone positioning improves oxygenation in patients with ARDS (1-3). Patients with severe ARDS due to COVID-19 are candidates for prone position. It should be started within 36-48 h and maintained 1, 3). Prone ventilationARDS based on a randomized trial that showed a mortality benefit (PROSEVA) (3). The improvement of oxygenation occurs by making ventilation more homogeneous, limiting ventilator-associated lung injury (4-6). Prone positioning was as effective in improving oxygenation, static respiratory system compliance (Crs) (7). Higher PEEP should be applied when there is a high recruitability potential of the lung. This study aimed to investigate whether prone positioning changes the recruitability position of the lung.in COVID-ARDS.

Clinical Trial Description

Prone positioning improves oxygenation in patients with ARDS (1-3). Patients with severe ARDS due to COVID-19 are candidates for prone position. It should be started within 36-48 h and maintained 1, 3). Prone ventilationARDS based on a randomized trial that showed a mortality benefit (PROSEVA) (3). The improvement of oxygenation occurs by making ventilation more homogeneous, limiting ventilator-associated lung injury (4-6). Prone positioning was as effective in improving oxygenation, static respiratory system compliance (Crs) (7).Higher PEEP should be applied when there is a high recruitability potential of the lung. This study aimed to investigate whether prone positioning changes the oxygenation, respiratory mechanics and recruitability position of the lung in COVID-ARDS. ;

Study Design

Related Conditions & MeSH terms

ARDS
Coronavirus Disease 2019
COVID-19
Mechanical Ventilation Pressure High

Clinical Trial Details

NCT number	NCT05150847
Study type	Interventional
Source	Tepecik Training and Research Hospital
Contact	KAZIM ROLLAS
Phone	+905532787535
Email	kazim.rollas@yahoo.com
Status	Recruiting
Phase	N/A
Start date	December 25, 2021
Completion date	April 13, 2022

View Details

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