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Clinical Application of Electrical Impedance Tomography for Individual Adjustment of Ventilator Settings — CLEAR  

ARDS Clinical Trial

Official title:
Pilot Clinical Study on Patient-Specific Adjustment of Ventilator Settings Using Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrome

Clinical Trial Summary

First clinical application of an algorithm for individual adjustment of ventilator settings using electrical impedance tomography.

Clinical Trial Description

In patients suffering from early Acute Respiratory Distress Syndrome (ARDS), an algorithm for individual adjustment of positive end-expiratory pressure and tidal volume will be applied. After optimization of ventilator settings according to the ARDS Network protocol, lung stress and strain, driving pressure, respiratory system compliance (Crs), regional ventilation delay and PaO2 / FiO2 ratio will be recorded. Subsequently, ventilator settings will be adjusted using an algorithm aiming at recruitment and avoiding tidal recruitment and overdistension using electrical impedance tomography (EIT). After 4 hours of EIT-based optimization ventilator settings, lung stress and strain, driving pressure, respiratory system compliance (Crs), regional ventilation delay and PaO2 / FiO2 ratio will be recorded again. The results will be compared to the ARDS Network approach. ;

Study Design

Related Conditions & MeSH terms

  • ARDS
  • Respiratory Distress Syndrome, Adult
Clinical Trial Details
NCT number NCT02703012
Study type Interventional
Source University of Schleswig-Holstein
Contact
Status Completed
Phase N/A
Start date January 2016
Completion date April 4, 2019
View Details
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