Evaluation of Clinical Characteristics and Pathological Findings in Patients With Suspected Appendicitis

Appendicitis Clinical Trial

Official title:

Evaluation of Demographic and Clinical Characteristics and Intraoperative and Pathological Findings in Patients With Suspected Appendicitis Who Underwent Appendectomy in 5 Azar Hospital in 2022

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06462846
• Other study ID #: 113867
• Status: Completed
• Start date: April 19, 2022
• Est. completion date: May 30, 2024

Study information

• Verified date: June 2024
• Source: Golestan University of Medical sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

As we know, one of the most common reasons for people to visit health centers and hospitals (15%) is abdominal pain, and appendicitis is at the top of their diagnosis in the 2-4th decade of age, which in most cases For treatment, considering the patient's condition and the need for surgery, appendectomy is the first method. One of the things that helps us a lot in this area is the epidemiology and incidence of this disease in the target society, which sometimes varies in different regions. One of the things that can be checked in this disease is the age and gender of the person and its incidence in different age ranges.

Description:

appendicitis is one of the most important reasons for people to go to the hospital, and 15% of the visits to the hospital are for this reason, and sometimes patients end up undergoing appendectomy. The mortality rate of this disease is 0.2-1% among young people and 8% among people over 65 years old In some people, depending on the sex, age, pregnancy and related diseases and even the weight of the people, the location of the appendix is different and this issue is very important during surgery. Different positions of the appendix, such as retro-scapular, subhepatic, pelvic, etc., create different challenges during surgery, so investigating the possibilities of the location of the appendix is an important issue in the decision-making and preparation of the patient and the surgical team.

Also, laboratory criteria such as wbc, diff, plt, crp can also help in diagnosing this disease. In this project, in addition to the above, the chief complaints and accompanying symptoms of people have also been examined

Recruitment information / eligibility

• Status: Completed
• Enrollment: 291
• Est. completion date: May 30, 2024
• Est. primary completion date: May 20, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• diagnosis of appendicitis

• appendectomy

Exclusion Criteria:

• Lack of required information in medical documents

Related Conditions & MeSH terms

• Appendicitis

Locations

Country	Name	City	State
Iran, Islamic Republic of	Golestan University of Medical Sciences, faculty of medicine	Gorgan	Golestan

Sponsors (1)

Lead Sponsor	Collaborator
Golestan University of Medical sciences

Country where clinical trial is conducted

Iran, Islamic Republic of, 

References & Publications (8)

Bayhan Z, Yildiz YA, Akdeniz Y, Gonullu E, Altintoprak F, Mantoglu B, Capoglu R, Kahyaoglu Akkaya Z. Appendix Neuroendocrine Tumor: Retrospective Analysis of 4026 Appendectomy Patients in a Single Center. Emerg Med Int. 2020 Sep 3;2020:4030527. doi: 10.1155/2020/4030527. eCollection 2020. — View Citation

Golz RA, Flum DR, Sanchez SE, Liu X, Donovan C, Drake FT. Geographic Association Between Incidence of Acute Appendicitis and Socioeconomic Status. JAMA Surg. 2020 Apr 1;155(4):330-338. doi: 10.1001/jamasurg.2019.6030. — View Citation

Henriksen SR, Rosenberg J, Fonnes S. Other Pathologies Were Rarely Reported after Laparoscopic Surgery for Suspected Appendicitis: A Systematic Review and Meta-Analysis. Dig Surg. 2023;40(3-4):91-99. doi: 10.1159/000531283. Epub 2023 Jul 18. — View Citation

Jukic M, Nizeteo P, Matas J, Pogorelic Z. Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study. Children (Basel). 2023 May 15;10(5):887. doi: 10.3390/children10050887. — View Citation

Lee JH, Park YS, Choi JS. The epidemiology of appendicitis and appendectomy in South Korea: national registry data. J Epidemiol. 2010;20(2):97-105. doi: 10.2188/jea.je20090011. Epub 2009 Dec 19. — View Citation

Pineda Villeda RH, Flores Reyes DL, Suazo Rivera JF. Acute Appendicitis: Epidemiological, Clinical, Surgical, and Post-surgical Characteristics in a Honduran General Hospital. Cureus. 2023 Jun 14;15(6):e40428. doi: 10.7759/cureus.40428. eCollection 2023 J — View Citation

Tavra A, Quien D, Barcot O. Oncological aspect of incidental appendectomy with regard to histopathological findings: A retrospective cohort study. Eur J Surg Oncol. 2023 Oct;49(10):107013. doi: 10.1016/j.ejso.2023.107013. Epub 2023 Aug 11. — View Citation

Yagmur Y, Sogutcu N, Gumus S. Recent classifications systems for gastroenteropancreatic neuroendocrine tumors A single-center experience. Ann Ital Chir. 2020;91:598-604. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The accuracy of imaging in determining the size of the appendix in patients with suspected appendicitis	comparison of the appendix size reported in radiologic studies with pathologic findings	One year
Secondary	correlation between CRP levels and pathologic findings in patients with suspected appendicitis	Comparison of CRP levels in the different stages of appendicitis according to pathologic reports	One year
Secondary	correlation between WBC measures and pathologic findings in patients with suspected appendicitis	Comparison of WBC measures in the different stages of appendicitis according to pathologic reports	One year
Secondary	sex distribution in patients with suspected appendicitis	the prevalence and percentage of each sex group in patients with suspected appendicitis	one year
Secondary	Age distribution in patients with suspected appendicitis	the prevalence and percentage of each age group in patients with suspected appendicitis	one year
Secondary	prevalence of clinical findings in patients with suspected appendicitis	prevalence and percentage of each clinical finding (fever, anorexia, shifting pain, tenderness, rebound tenderness, rovsing sign, psoas sign) in patients with suspected appendicitis	one year