TRIAD Appendicitis Decision-making Surveys

Status Recruiting

Clinical Trial Summary

While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients with appendicitis. This information will be used to inform the design of decision-support interventions to help patients improve their ability to make an informed decision in-line with their preferences and values.

Clinical Trial Description

TRIAD Patient Surveys is a cross-sectional survey design that will lead to more informed decision making and better outcomes related to antibiotics for appendicitis. TRIAD was developed from questions raised by the University of Washington CODA Trial that addressed many of the methodological issues in the European studies and included diverse, adult patients (n=1552) with almost all types of presentations of appendicitis. TRIAD surveys will be carried out in clinics and hospitals across the United States. Patients who are diagnosed with appendicitis will be recruited for study participation regardless of which treatment (appendectomy or antibiotics) they receive. Investigators invite patients to participate in a survey designed to identify awareness of treatment options and levels of decisional conflict (measured with the Ottawa Decisional Conflict Score [DCS]). Participants will complete a baseline survey via a convenient electronic platform, and follow-up surveys will be sent at 30 days. By implementing the TRIAD surveys, researchers hope to obtain a better understanding of patients' perspectives, knowledge, and decision-making processes regarding the choice between appendectomy and antibiotic treatment for appendicitis. This data can contribute to more informed decision-making and potentially improve outcomes related to antibiotic use for this condition. ;

Study Design

Related Conditions & MeSH terms

Appendicitis

Clinical Trial Details

NCT number	NCT05887414
Study type	Observational
Source	University of Washington
Contact	Sara DePaoli
Phone	206-543-8624
Email	sdepaoli@uw.edu
Status	Recruiting
Phase
Start date	October 1, 2022
Completion date	October 1, 2025

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04529980` - Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis	N/A
Withdrawn	`NCT03528343` - Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy	Phase 1/Phase 2
Recruiting	`NCT03522233` - Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
Recruiting	`NCT03380793` - A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis	Phase 4
Recruiting	`NCT02108340` - Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis	N/A
Terminated	`NCT02029781` - The Laparoscopic Appendicitis Score; a Multicenter Validation Study	N/A
Completed	`NCT01356641` - Antibiotic Treatment Alone for Acute Simple Appendicitis in Children	N/A
Terminated	`NCT00971438` - Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging	N/A
Completed	`NCT01515293` - Single Incision Versus Conventional Laparoscopic Appendectomy	Phase 3
Completed	`NCT00913380` - Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT	Phase 3
Completed	`NCT00616616` - Single Incision Laparoscopy	N/A
Completed	`NCT00530998` - Minimally Invasive Surgery: Using Natural Orfices
Completed	`NCT00195351` - Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection	Phase 4
Completed	`NCT02916134` - Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis	N/A
Completed	`NCT04614649` - Right Iliac Fossa Treatment-Turkey Audit
Completed	`NCT04365491` - European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Completed	`NCT03770897` - Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome	N/A
Completed	`NCT02507674` - Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study
Active, not recruiting	`NCT01718275` - Non-operative Management of Early Appendicitis in Children
Terminated	`NCT01575028` - Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies	Phase 2

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

TRIAD Appendicitis Decision-making Surveys — TRIAD

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms