Appendicitis Clinical Trial
Official title:
CT Scan Using IV Contrast Alone for Pediatric Appendicitis
Verified date | July 2008 |
Source | University of Rochester |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Interventional |
Computed tomography (CT) scan using intravenous contrast (CT IV) as the sole type of
contrast material, was studied as one method of evaluating children with suspected
appendicitis. We felt that this technique could provide physicians with a faster and
better-tolerated alternative to CT imaging which involves patients drinking oral contrast or
needing rectal contrast administered.
SPECIFIC AIMS
1. To test an imaging protocol using CT IV for the evaluation of suspected appendicitis in
children in the setting of a pediatric emergency department (ED).
2. To determine test performance characteristics (specificity, sensitivity and diagnostic
accuracy) of CT IV in detecting appendicitis in children.
Status | Completed |
Enrollment | 250 |
Est. completion date | October 2005 |
Est. primary completion date | October 2005 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 3 Years to 18 Years |
Eligibility |
Inclusion Criteria: - Age 3- 18 years - Signs/symptoms for < 72 hours - CT Scan requested for evaluation by attending or fellow Exclusion Criteria: - Clinically apparent appendicitis - Pregnancy - Sickle Cell Disease - Known contrast allergy - Previous enrollment - Signs/symptoms for > 72 hrs - Known abdominal disease (e.g. Crohn's) - Exam unreliable (neurologically impaired patient) |
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
United States | University of Rochester | Rochester | New York |
Lead Sponsor | Collaborator |
---|---|
University of Rochester |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Sensitivity, Specificity, PPV, NPV for CT Scan with IV contrast alone | Study completion date | No | |
Secondary | Time to CT scan for CT with IV contrast alone v. CT using both IV and oral contrast | study completion date | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04529980 -
Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis
|
N/A | |
Withdrawn |
NCT03528343 -
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
|
Phase 1/Phase 2 | |
Recruiting |
NCT03522233 -
Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
|
||
Recruiting |
NCT03380793 -
A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis
|
Phase 4 | |
Recruiting |
NCT02108340 -
Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis
|
N/A | |
Terminated |
NCT02029781 -
The Laparoscopic Appendicitis Score; a Multicenter Validation Study
|
N/A | |
Completed |
NCT01356641 -
Antibiotic Treatment Alone for Acute Simple Appendicitis in Children
|
N/A | |
Completed |
NCT00913380 -
Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT
|
Phase 3 | |
Terminated |
NCT00971438 -
Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging
|
N/A | |
Completed |
NCT01515293 -
Single Incision Versus Conventional Laparoscopic Appendectomy
|
Phase 3 | |
Completed |
NCT00530998 -
Minimally Invasive Surgery: Using Natural Orfices
|
||
Completed |
NCT00616616 -
Single Incision Laparoscopy
|
N/A | |
Completed |
NCT00195351 -
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection
|
Phase 4 | |
Completed |
NCT02916134 -
Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis
|
N/A | |
Completed |
NCT04614649 -
Right Iliac Fossa Treatment-Turkey Audit
|
||
Completed |
NCT04365491 -
European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
|
||
Completed |
NCT03770897 -
Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome
|
N/A | |
Completed |
NCT02507674 -
Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study
|
||
Active, not recruiting |
NCT01718275 -
Non-operative Management of Early Appendicitis in Children
|
||
Terminated |
NCT01575028 -
Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies
|
Phase 2 |