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NCT00630071 Clinical Trial

Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis

Appendicitis Clinical Trial

Official title:
A Prospective Study Investigating the Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00630071
Other study ID # PCT 01
Secondary ID
Status Completed
Phase N/A
First received February 26, 2008
Last updated October 15, 2012
Start date February 2008
Est. completion date August 2008

Study information
Verified date October 2012
Source Ruhr University of Bochum
Contact n/a
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

The values of laboratory examinations which are useful for the diagnoses of acute appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR). Another laboratory value which has recently received considerable attention for the early diagnosis of bacterial infection and sepsis is pro-calcitonin (PCT). In recent studies it has been clearly shown that PCT is one of the most important biochemical indicators which closely correlates with the severity of inflammatory host response to microbial infections. Aim of this open, prospective study is therefore to investigate if PCT has an accurate diagnostic value for the diagnosis of acute appendicitis.

Recruitment information / eligibility
Status Completed
Enrollment 103
Est. completion date August 2008
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 14 Years and older
Eligibility Inclusion Criteria:

- Clinical diagnosis of appendicitis

Exclusion Criteria:

- Antibiotic therapy

- Infection at other body sites

- Age < 14 years

- Appendectomy in the medical history

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Germany Department of General and Visceral Surgery, Augusta Krankenanstalt, Academic Teaching Hospital of the Ruhr-University Bochum, Germany Bochum

Sponsors (1)
Lead Sponsor Collaborator
Ruhr University of Bochum

Country where clinical trial is conducted

Germany, 

References & Publications (1)

Sand M, Trullen XV, Bechara FG, Pala XF, Sand D, Landgrafe G, Mann B. A prospective bicenter study investigating the diagnostic value of procalcitonin in patients with acute appendicitis. Eur Surg Res. 2009;43(3):291-7. doi: 10.1159/000232939. Epub 2009 A — View Citation

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