Closure of the Appendiceal Stump

Status Not yet recruiting

Clinical Trial Summary

Laparoscopic appendectomy is a well-defined surgical technique. However, concerns remain about whether closure of the appendiceal stump should be done with clips, endoloops, staples, or other techniques. If tying is to be used in the closure of the appendiceal stump, there is no consensus on which technique (intracorporoyal, extracorporoyal, etc.) should be used for ligation. For this reason, there is a need for studies on different binding techniques and instruments currently used. The aim of this study was to compare the use of unilateral intracorporeal knot and polymer endoclip closure during laparoscopic appendectomy.

Clinical Trial Description

Patients who are scheduled to undergo laparoscopic appendectomy after the ethics committee approval will be included consecutively. Patients will be randomized into 2 groups: those who will be closed with a polymer endoclip (Group 1) and those who will be closed with an intracorporeal node with a single instrument (Group 2). Data such as age, gender, body mass index, comorbidities, previous abdominal surgeries, medications used by the patients, as well as the presence of ileus, perforation, and diffuse peritonitis will be recorded. After laparoscopic dissection, the appendiceal stump will be closed with a polyper homologous clip in Group 1 and the stump will be closed with an intracorporial node with a single instrument in Group 2. The operation times of the patients, the time elapsed after the end of the dissection until the pathology specimen comes out of the skin (to be determined as the closure time), complications such as ileus, intra-abdominal abscess, bleeding and fistula related to stump closure problems encountered in the postoperative period will be recorded and compared. Patients will be followed by the corresponding author In both surgical methods, it is routinely used to close the appendiceal stump and in the polymer clip application, a clip with a locking mechanism is used when the stump is tightened with an applicator. In the intracorporial node with one hand, the surgical node is made by circulating the tip of the suture material around the appendix with a single instrument (the other end is kept fixed outside the abdomen) ;

Study Design

Related Conditions & MeSH terms

Appendectomy

Clinical Trial Details

NCT number	NCT06443749
Study type	Interventional
Source	Kahramanmaras Sutcu Imam University
Contact	Sezgin Topuz
Phone	+905370252264
Email	sezgintpz@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	August 2024
Completion date	December 2024

View Details

See also
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Not yet recruiting	`NCT04294537` - TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study	N/A
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Completed	`NCT05099302` - The Effect of Cartoons Watched Before Surgery on Children's Fear Level	N/A
Completed	`NCT04614519` - Appendectomy by Low Impact Laparoscopy vs Routine Laparoscopy : a Randomized Prospective Monocentric Trial	N/A
Completed	`NCT06407622` - The Effect of Foot Reflexology on Patients Undergoing Appendectomy Surgery	N/A
Completed	`NCT03947372` - Comparison of Outcomes After Laparoscopic Versus Open Appendectomy in Acute Appendicitis	N/A
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Recruiting	`NCT04464382` - Evaluating the Safety and Efficacy of a Outpatient Appendectomy	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.