Apneic Oxygenation Clinical Trial
Official title:
A "Less-rapid" Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the "Duration of Apnea Without Desaturation" in Paralyzed Non-obese and Morbidly Obese Patients?
The study will test the efficacy of the Pentax AWSTM video laryngoscope (VLS) equipped with a P Blade (Figure 1) as the means to provide Apneic Oxygenation (AO) and prolong Duration of Apnea Without Desaturation (DAWD) in non-obese and morbidly obese females.
Pre-oxygenation/de-nitrogenation for three minutes of spontaneous breathing or alternatively
four to eight deep breaths prior to rapid sequence anesthetic induction/intubation (RSII) in
patients with healthy lungs, low oxygen demands and normal hemoglobin levels allows up to
eight minutes of safe apnea time or DAWD.
The study will test the efficacy of the Pentax AWSTM video laryngoscope (VLS) equipped with a
P Blade as the means to provide apneic oxygenation and prolong DAWD. The P Blade sports a
suction conduit which can equally well provide a conduit for oxygen administration. The
initial phase of the study will include non-obese healthy (ASAR 1-2) women patients requiring
endotracheal anesthesia for gynecologic (open or laparoscopic) abdominal surgery.
Subsequently a cohort of morbidly obese patients (BM I ≥ 40 kg/m2) also requiring gynecologic
abdominal access will be recruited for investigation.
Participants of each group (obese, non-obese) will be randomized to apneic oxygenation with
the the Pentax AWS Laryngoscope or no apneic oxygenation.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02755389 -
Apneic Oxygenation Via Nasal Cannulae: 15 L/Min vs High-Flow
|
Phase 4 | |
| Not yet recruiting |
NCT04242537 -
Apneic Oxygenation in the Emergency Department
|
N/A | |
| Terminated |
NCT03694379 -
Apneic Oxygenation Including Precipitous Intubations During RSI in the ED
|
N/A | |
| Terminated |
NCT05234424 -
Flow Rate Impact on Arterial Carbon Dioxide During THRIVE
|
N/A | |
| Completed |
NCT03629353 -
The Efficacy of Transnasal Humidified Rapid-insufflation Ventilatory Exchange During Laryngeal Microsurgery
|
N/A | |
| Completed |
NCT03195504 -
High-flow Nasal Oxygenation in Obese Patients During Apnea
|
N/A |