Clinical Trials Logo
  1. Home
  2. Apnea, Sleep
  3. NCT01092780

Pharmacodynamics and Efficacy of MK-7288 in Adults With Sleep Apnea (MK-7288-010)

Apnea, Sleep Clinical Trial

Official title:
An Active-Comparator Controlled Single Dose Study to Evaluate the Pharmacodynamics/Efficacy of MK-7288 in Sleep Apnea Patients

Clinical Trial Summary

This is a study of the safety and efficacy of MK-7288 for the treatment of excessive daytime sleepiness (EDS) in participants with obstructive sleep apnea (OSA)/hypopnea syndrome (HS) who are compliant with effective nasal continuous positive airway pressure (nCPAP) therapy. The goal of this study is to determine the effect of MK-7288 after single dose administration on promoting wakefulness as measured by sleep latency on Maintenance of Wakefulness Tests, and on driving performance as measured by standard deviation of lane position in simulated driving (country vigilance driving).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01092780
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Completed
Phase Phase 1
Start date May 26, 2010
Completion date May 31, 2011
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04326634 - Controlled Exercises Effectiveness in Patients With Sleep Apnea N/A
Completed NCT02898792 - Remifentanil in Adults With OSA Early Phase 1
Active, not recruiting NCT04861038 - Study Using Negative Pressure to Reduce Apnea N/A
Completed NCT00252629 - Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment N/A
Completed NCT03033901 - Comparison of Sleep Apnea Assessment Strategies to Maximize TBI Rehabilitation Participation and Outcome
Completed NCT02349893 - Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm, Multicenter Study N/A
Completed NCT03034447 - Sleep Apnea in Asthmatic Children and Teenagers N/A
Completed NCT03172806 - Comparison of the New Algorithm of STOP-Bang in the Detection of Severe OSA Patients
Completed NCT02886156 - Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial N/A