Aphasia Clinical Trial
Official title:
A Novel Treatment for Aphasia and Apraxia of Speech: Measurement of Outcomes
In order to determine if speech-language therapy has positive effect, reliable measurement
tools are required to document outcomes. Currently, there is very limited information
concerning the measurement of changes in speech production as a result of treatment for
acquired apraxia of speech and aphasia. This study will obtain information concerning the
reliability of several speech production measures over time. Thirty persons with chronic
aphasia and apraxia of speech will be asked to provide speech samples in response to commonly
used assessment tools on three sampling occasions so that the stability of measurements may
be examined.
After establishment of appropriate outcome measures, a small, pilot treatment study will be
conducted with four participants. The participants will receive a new treatment for aphasia
and acquired apraxia of speech and outcomes will be measured relative to speech and language
production.
A single group, repeated measures design will be used to obtain repeated speech samples from
30 persons with chronic acquired apraxia of speech and aphasia. Speech samples will be
elicited using commonly employed motor speech assessment protocols; an initial sample, a
sample one week following the initial sample, and a sample at four weeks following the
initial sample. The following measures will be obtained from the samples: percent consonants
correct, percent fluent utterances, and duration of utterance. Stability of the measures will
be examined.
After the preceding measures have been analyzed, a series of four, single-subject
experimental designs will be conducted. Four participants with chronic aphasia and apraxia of
speech will receive a new treatment for aphasia and apraxia of speech applied sequentially to
two sets of experimental picture picture stimuli. Outcomes will be measured in terms of
speech production (measures described above) as well as in terms of language production.
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