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Expression of Sodium-glucose Co-transporter 2 in Human Heart — SGLT2-MICRA  

Aortic Valve Stenosis Clinical Trial

Official title:
Expression of Sodium Glucose Co-transporter2 in Myocardium From Patients With Aortic Valve Stenosis and With/Without Diastolic Heart Failure

Clinical Trial Summary

The aim of the study is to evaluate the expression of Sodium Glucose Co-transporter 2 (SGLT2) in myocardium from patients with aortic stenosis. 2 groups of patients will be defined: Group A with diastolic heart failure and Group B without heart failure. The expression of SGLT2 will be measured on small myocardium specimens harvested during aortic valve replacement operation. This study should allow us to better understand the effect of glifozines in human heart failure.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05830760
Study type Interventional
Source University Hospital, Strasbourg, France
Contact Jean Philippe MAZZUCOTELLI, Professor
Phone 369555703
Email Jean-Philippe.MAZZUCOTELLI@chru-strasbourg.fr
Status Not yet recruiting
Phase N/A
Start date June 2023
Completion date October 2025
View Details
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