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Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis — ELASTOP-AS  

Aortic Valve Stenosis Clinical Trial

Official title:
Epicardial Measurement of Myocardial Stiffness on Beating Heart and Non-beating Heart During a Programmed Surgical Aortic Valve Replacement for Aortic Stenosis

Clinical Trial Summary

Elastography is a new non-invasive medical technique for measuring the stiffness at a distance from a tissue. Recent advances in the development of elastography sequences for cardiac exploration suggest a more clinical approach to cardiac elastography. This study propose to compare myocardial stiffness of a group of coronary bypass patients without hypertrophic left ventricular remodeling or sequelae of myocardial infarction versus a group of patients who should benefit from a surgical aortic valve replacement for aortic stenosis. The hypothesis is that the physiological adaptation to pressure overload constituted by aortic stenosis is responsible for a significant increase in myocardial stiffness compared to a reference group.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04358692
Study type Interventional
Source University Hospital, Rouen
Contact Hélène Eltchaninoff, MD
Phone 0232888232
Email helene.eltchaninoff@chu-rouen.fr
Status Recruiting
Phase N/A
Start date June 30, 2020
Completion date June 30, 2024
View Details
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