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HEParin Antagonisation in Transcatheter Aortic Valve Implantation — HepaTAVI  

Aortic Valve Stenosis Clinical Trial

Official title:
Heparin Influence on Anticoagulation and Perioperative Hemostasis During Transfemoral Transcatheter Aortic Valve Implantation

Clinical Trial Summary

Unfractioned heparin is usually given in a defined dosage during transfemoral TAVI. Activated Clotting Time (ACT) is usually used to measure the heparin effect. ACT-analysis is easy to perform at the bedside, but susceptible to interference effects. At the end of the procedure, protamine is given to reverse eventual residual heparin effect. An overdose of protamine can impair the coagulation itself. The investigators want to analyse the effect of a partial heparin reversal by ROTEM Analysis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05422170
Study type Observational
Source Deutsches Herzzentrum Muenchen
Contact Patrick Mayr, MD
Phone +498912180
Email mayrp@dhm.mhn.de
Status Not yet recruiting
Phase
Start date July 1, 2022
Completion date April 1, 2023
View Details
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