Aortic Dissection Clinical Trial
— VaRALADOfficial title:
A Validation Study of The Relationship Between ALDH2 and Aortic Dissection
The purpose of this study is to validate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.
| Status | Recruiting |
| Enrollment | 200 |
| Est. completion date | September 30, 2019 |
| Est. primary completion date | September 30, 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | N/A and older |
| Eligibility |
Inclusion Criteria: - Chinese Han people diagnosed with aortic dissection in Guangdong Provincial People's Hospital Exclusion Criteria: - Aortic dissection based on trauma, connective tissue diseases and pregnancy - Patients with tumor - Patients with no written consensus |
| Country | Name | City | State |
|---|---|---|---|
| China | Guangdong Provincial People's Hospital | Guanzhou | Guangdong |
| Lead Sponsor | Collaborator |
|---|---|
| Qilu Hospital of Shandong University |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Number of patients with different ALDH2 genotype | DNA was extracted from venous blood;genomic DNA underwent PCR amplification; finally, PCR products were purified and directly sequenced by Invitrogen Corp or Biosune Corp.Then ALDH2 genotype was distinguished depend on a G-to-A missense mutation on exon 12 of ALDH2 gene. | 1-30 days after samples collected |
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05582967 -
The DAShED (Diagnosis of Aortic Syndrome in the ED) Study
|
||
| Terminated |
NCT04116684 -
Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients
|
N/A | |
| Completed |
NCT02086136 -
Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection
|
||
| Recruiting |
NCT02201589 -
Feasibility of Endovascular Repair Of Ascending Aortic Pathologies
|
N/A | |
| Recruiting |
NCT03948555 -
Magnetic Resonance Imaging (MRI) for Aortic Dissection to Visualise Inflammation
|
||
| Enrolling by invitation |
NCT05912608 -
Optimal Strategy for Repair of Type A Acute Aortic Dissection
|
||
| Recruiting |
NCT03707743 -
Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE)
|
||
| Enrolling by invitation |
NCT00583817 -
Endovascular Treatment of Thoracic Aortic Disease
|
N/A | |
| Recruiting |
NCT05073991 -
Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.
|
||
| Not yet recruiting |
NCT02523300 -
Glucocorticoid on the Prognosis of TEVAR
|
N/A | |
| Completed |
NCT01197651 -
Aortic-Stent-Register
|
N/A | |
| Recruiting |
NCT04471909 -
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
|
N/A | |
| Not yet recruiting |
NCT06044259 -
Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection
|
N/A | |
| Completed |
NCT05039814 -
Prediction of Postoperative Acute Kidney Injury in Patients With Acute Type A Aortic Dissection Using Cystatin C
|
||
| Completed |
NCT03647566 -
18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
|
||
| Enrolling by invitation |
NCT05800743 -
Evaluation of the GORE® Ascending Stent Graft
|
N/A | |
| Recruiting |
NCT03347812 -
Clinical Study for Evaluating the Safety and Efficacy of Total Endovascular Aortic Arch Repair
|
N/A | |
| Completed |
NCT05044494 -
Surgery for Delay-recognized or Defer-operated Type A Aortic Dissection
|
||
| Terminated |
NCT02958098 -
My Research Legacy Pilot Study
|
||
| Recruiting |
NCT04450433 -
Functional Study of Metabolites in Patients With Aortic Dissection
|