Aortic Aneurysm Clinical Trial
Official title:
Laser In Situ Fenestration for Endovascular Aortic Repair (LIFE) Study
The goal of this clinical trial is to learn about a new device, named the LIFE device, to treat people with aneurysms (swellings) in the aorta (large, main blood vessel that delivers blood from the heart to the body). The main questions this trial aims to answer are: - If the LIFE device works to treat aortic aneurysms - What medical problems participants have when the LIFE device is used Participants will undergo treatment with the LIFE device and thereafter at 30 days, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years have their pulses checked, bloodwork to check kidney function (BUN and serum creatinine), and a CT scan of the aneurysm area.
In this clinical trial the LIFE device is used to treat people with aneurysms in the aorta near the kidney arteries (called juxtarenal or pararenal aortic aneurysms). Tubes, called stent grafts, are typically inserted through blood vessels in the groin and placed inside the aorta in the abdomen and chest area (endovascularly placed) to cover the tear or leak in the aorta. The LIFE device covers the tear or leak and has side branches to let blood flow into the kidney, spleen, intestine, or liver arteries. Participants in this study are not candidates for endovascular devices approved for endovascular aorta repair to the juxtarenal or pararenal aorta, not candidates for open repair, not willing to travel to sites that have access to manufacturer-made endovascular devices, and patients for whom there are no favorable alternatives, for example, urgent, symptomatic, and emergency cases. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04149600 -
Identification of Genetic Causes of Calcific Aortic Valve Disease
|
||
| Enrolling by invitation |
NCT04035356 -
HAART Annuloplasty Device Valve Repair Registry
|
||
| Recruiting |
NCT02729064 -
Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose
|
Phase 1 | |
| Completed |
NCT02467062 -
Implementation of Non-size Markers Derived From 4D Flow MRI of Patients With Aortic Disease.
|
N/A | |
| Completed |
NCT02283307 -
Dual Energy CT Urography With Reduced Iodinated Contrast
|
N/A | |
| Completed |
NCT01678261 -
X-chromosome Inactivation, Epigenetics and the Transcriptome
|
N/A | |
| Terminated |
NCT01055275 -
Cook Iliac Branch Graft Post-market Registry
|
N/A | |
| Completed |
NCT00615888 -
Fast Track Management in Elective Open Infrarenal Aortic Aneurysm Repair
|
N/A | |
| Completed |
NCT03510793 -
Microcirculation and Anesthesia in Vascular Surgery
|
||
| Completed |
NCT03207568 -
RE-GENERATION: The Safety and Performance of the Relay Pro and Relay NBS Pro Stent-graft Devices in the European Union (EU)
|
N/A | |
| Recruiting |
NCT05073991 -
Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.
|
||
| Not yet recruiting |
NCT01918969 -
Reference Values of Circulating Endothelial Progenitor Cells
|
N/A | |
| Not yet recruiting |
NCT01918982 -
Circulating Endothelial Progenitor Cells and Aortic Aneurysm
|
N/A | |
| Completed |
NCT02000544 -
Clinical Evaluation of a Modular Extracorporeal Circulation Circuit
|
N/A | |
| Completed |
NCT01256372 -
An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery
|
Phase 2 | |
| Recruiting |
NCT00661518 -
PET/CT Imaging of Aneurysm Wall Inflammation
|
N/A | |
| Completed |
NCT00094575 -
Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)
|
Phase 4 | |
| Recruiting |
NCT04471909 -
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
|
N/A | |
| Recruiting |
NCT05603520 -
Phenotyping Heterogeneity and Regionality of the Aorta
|
||
| Completed |
NCT03727542 -
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels
|
N/A |