AOD Use, Abuse, and Dependence Clinical Trial
Official title:
The Effects of Intranasal Oxytocin on Social Cognition, Implicit Preferences and Craving in Moderate to Heavy Social Alcohol Drinkers
This is a randomized, placebo controlled, double blind crossover study of the effects of intranasal oxytocin on social cognition, implicit preferences and craving in moderate to heavy social alcohol drinkers.
Impaired social functioning is an important feature of substance use disorders. Social
deficits are a risk factor for developing substance use disorders as well as a consequence
of substance abuse. Improved social functioning is also a key goal of effective substance
abuse treatments. While treatment of disrupted social networks is a mainstay of psychosocial
substance abuse treatments, there are currently no pharmacological interventions aimed at
improving social functioning in individuals with substance use disorders. Oxytocin
administration may shift preference from substance related cues to social cues and may
decrease subjective craving for alcohol.
The specific aims are:
1. To examine the effects of intranasal oxytocin administration on social cognition in
moderate to heavy social alcohol drinkers.
2. To examine the effects of intranasal oxytocin administration on alcohol craving.
3. To examine the effects of intranasal oxytocin administration on implicit preferences
for drug-related and social stimuli in moderate to heavy social alcohol drinkers.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02227589 -
Treatment for Teens With Alcohol Abuse and Depression
|
N/A |