Antiphospholipid Syndrome Clinical Trial
Official title:
Detection Of Anti-Double Stranded Deoxyribonucleic Acid Antibodies In Autoimmune Rheumatic Diseases: Comparison Between Immunofluorescence And Enzyme Immunoassay
Verified date | September 2017 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
detection of anti-ds DNA in patients with rheumatic diseases by two methodes : immunofluorescence & ELISA
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | October 1, 2019 |
Est. primary completion date | September 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 70 Years |
Eligibility |
Inclusion Criteria: - The study will include patients with suspected diagnosis of autoimmune rheumatic diseases referred to the Laboratory of Clinical Immunology, Clinical Pathology Department, Assiut University Hospital for anti-dsDNA test. Patients will be recruited into the study within period of one year. Also, apparently healthy subjects (at least 25 subjects; according to international method verification guidelines) will be included as a control group Exclusion Criteria: - Subjects refused to be included in the study. Patients without a definite diagnosis of autoimmune rheumatic disease |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Bai Y, Tong Y, Liu Y, Hu H. Self-dsDNA in the pathogenesis of systemic lupus erythematosus. Clin Exp Immunol. 2017 Aug 24. doi: 10.1111/cei.13041. [Epub ahead of print] Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Comparison Between Immunofluorescence and Enzyme Immunoassay | Verfication of the anti-dsDNA examination methods used in the Laboratory of Clinical Immunology, Assiut University Hospital. | one year | |
Secondary | Detection of Anti-Double Stranded Deoxyribonucleic Acid Antibodies in Autoimmune Rheumatic Diseases | Verfication of the anti-dsDNA examination | one year |
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